Yiyi Chen, PhD

Assistant Professor


BA (1998) Zhejiang University, Economics
MA (2001) Fudan University, Economics
MA (2004) University of Iowa, Economics
MS (2005) University of Iowa, Biostatistics
PhD (2008) University of Iowa, Biostatistics

Major Areas of research

Design and analysis of clinical trials; Bayesian statistics

Experience and Interests

Dr. Chen is a biostatistician with primary interest in oncology clinical trials and cancer research. Her current interest is in the decision rule for phase II oncology trials, and the application of Bayesian decision theory to physician-patient decision models.

Selected Publications

Chen Y and Smith BJ (2009). Adaptive Group Sequential Design for Phase II Clinical Trials: A Bayesian Decision Theoretic Approach. Statistics in Medicine 28: 3347-3362.

Tanyi JA, Summers PA, McCracken CL, Chen Y, Ku L-C and Fuss M (2009). Implications of a High-Definition Multi Leaf Collimator (HD-MLC) on Treatment Planning Techniques for Stereotactic Body Radiation Therapy (SBRT): a Planning Study. Radiation Oncology, 10, 4:22.

Polgreen PM, Chen Y, Beekmann S, Srinivasan A, Neill MA, Gay T and Cavanaugh JE (2008).  Elements of Influenza Vaccination Programs that Predict higher Vaccination Rates: Results of an Emerging Infections Network Survey.  Clinical Infectious Diseases, 46(1), 14-19.

Herwaldt LA, Appelgate D, Kuntz J, Chen Y and Pottinger J (2007). Infection Control Resources in Iowa. American Journal of Infection Control, 35(10), 662-665.

Quinn LK, Chen Y, and Herwaldt LA (2007).  Survey of Long-Term Care Facilities in Iowa for Policies and Practices Regarding Residents with Clostridium Difficile Infection.  Infection Control and Hospital Epidemiology, 28(11), 1228-1232.

Polgreen P, Chen Y, Cavanaugh J, Ward M, Coffman S, Hornick D, Diekema DJ, Herwaldt LA(2007). An Outbreak of Severe Clostridium Difficile-Associated Disease Possibly Related to Inappropriate Antimicrobial Therapy for Community-Acquired Pneumonia. Infection Control and Hospital Epidemiology, 28(2), 212-214.

Polgreen P, Beekmann SE, Chen Y, Doern GV, Pfaller MA, Brueggemann AB, Herwaldt LA, Diekema DJ (2006). Epidemiology of Methicillin-Resistant Staphylococcus Aureus and Vancomycin-Resistant Enterococcus in a Rural State. Infection Control and Hospital Epidemiology, 27(3), 252-256.

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Phone: 503-346-0790

Address: 3181 SW Sam Jackson Park Road

Mail code: CR-145

Portland, Oregon 97239-3098

Email Dr. Chen


Visit Dr. Chen's Biostatistics page, where you can compute the testing confidence value based transitional decision rule for single-arm phase II trials.