MR Gaucher Research Protocol

Revised - 9/16/2014
Charge for what you scan: Abdomen / Pelvis / Femur / L-spine WO, "No protocol required"

RM1 or 2 ONLY- torso array coil and spine coil used

Jump to:   Abdomen - Pelvis - Femur - LSpine

What would Joe do? (WWJD)

First, look in the order to see which order has been requested: There are TWO RIS order versions for this exam: - Research – will also be called the Actelion Gaucher Study (Perform only on Room 1) - Diagnostic (Perform on either Room 1 or 2)
These are never performed at CHH.
The entire protocol is the same regardless of whether or not the exam is a research study or not.
The only difference is which scanner it is performed on.
The Abdomen scans are breath-holds. You can change parameters as needed to get a single acquisition. HOWEVER - you CANNOT change the slice thickness / gap. (The slice thickness/gap need to add up to 10 - i.e. 8 skip 2, 9 skip 1, etc.) When done let CT know that you need liver volumes calculated on this subject.
The protocols are found in the research folder.
We don't always do all four of these (e.g. sometimes they don't do the pelvis sequences), so just perform the stations as ordered.
The total scan time for all 4 stations is about an hour to an hour and a half, but our schedulers like to put these in much longer blocks and tell the patients it's like 4 hours. So make sure the subject knows it's fairly short.
Abdomen- 8ch Torso Array Coil
Sequence   Change Parameters? Change # slices? Coverage/ Angulation
AX
T1 TR only YES Angle as normal, be sure to cover the entire mass/tumor/pit
AX T1 TR only YES Angle as normal, be sure to cover the entire mass/tumor/pit
Notes: These scans are breath-holds. You can change parameters as needed to get a single acquisition. HOWEVER - you CAN NOT change the slice thickness / gap. (The slice thickness/gap need to add up to 10 - i.e. 8 skip 2, 9 skip 1, etc.) When done let CT know that you need liver volumes calculated on this subject.
Gaucher Protocol - CT image Liver Volume that CT generates
Pelvis- 8ch Torso Array Coil
Sequence   Change Parameters? Change # slices? Coverage/ Angulation
COR
STIR YES YES Cover Pelvis - Iliac Crest through lesser Trochantors. Skin to Skin A to P.
COR
T1 YES YES Cover Pelvis - Iliac Crest through lesser Trochantors. Skin to Skin A to P.
AX T1 YES YES Cover Pelvis - Iliac Crest through lesser Trochantors. Skin to Skin A to P.
AX T2 + fatsat
YES YES Cover Pelvis - Iliac Crest through lesser Trochantors. Skin to Skin A to P.
Notes: You can change the number of slices, TR, FoV, etc. to get scan into a single acquisition.
DO NOT CHANGE SLICE THICKNESS OR GAP.
 Gaucher Protocol Pelvis
Femur- 8ch Torso Array Coil
Sequence   Change Parameters? Change # slices? Coverage/ Angulation
COR T1 YES YES Cover from hip joint to knee joint in a single FoV
COR T2 YES YES Cover from hip joint to knee joint in a single FoV
COR STIR YES YES Cover from hip joint to knee joint in a single FoV
Notes: Must cover entire femur (including femoral head and femoral condyles – it’s okay if femoral heads are only imaged on the pelvic portion of the exam, if a dedicated Pelvis MR was also done). This is because the grading system takes marrow signal in both the proximal and distal femora into account.
You can change the number of slices, TR, FoV, etc. to get scan into a single acquisition.
DO NOT CHANGE SLICE THICKNESS OR GAP.
 Gaucher Femur
Lumbar Spine- Spine Coil
Sequence   Change Parameters? Change # slices? Coverage/ Angulation
SAG T1 YES YES Cover from T12 to S1.
T2 YES YES Cover from T12 to S1.
Notes: You can change the number of slices, TR, FoV, etc. to get scan into a single acquisition.
DO NOT CHANGE SLICE THICKNESS OR GAP.
Gaucher Spine