MR BIOGEN 101MS326 / "ASCEND" / Tysrabi Research Protocol

Revised - 9/16/2014
Charge as Brain WWO, "No protocol required", YES READ

What would Joe do? (WWJD)
The study drug is Tysrabi, so it may accidentally be called the “Tysrabi Study”.
Dosing is to the 10th (e.g 0.1) with NO MAXIMUM dosing (can give MORE THAN 10mL)

A note about the injection:

  1. Contrast should be administered over a 1 minute period.
  2. There should be a 10 minute delay from the END of contrast injection to the start of the 3DT1 Post sequence
RM 3 Only- 8ch Head Coil
Sequence   Change Parameters? Change # slices? Coverage/ Angulation Notes
SAG MIDLINE NO NO To True Midline  
AX
TEST NO NO To AC-PC Line  
AX PD NO NO To AC-PC Line  
AX T2 NO NO To AC-PC Line
AX
3DT1 NO NO To AC-PC Line Coverage to include 2-3 slices of air above the top of the head
Contrast Injection
  1. Contrast should be administered over a 1 minute period.
  2. There should be a 10 minute delay from the END of contrast injection to the start of the 3DT1 post sequence
AX POST FLAIR NO NO To AC-PC Line  
AX POST 3DT1 NO NO To AC-PC Line Start this sequence 10 minutes AFTER THE END of the contrast injection