Ross Martini receives MRF Grant

10/23/14  Portland, OR

Please join me in congratulating Dr. Ross Martini on receiving a Medical Research Foundation (MRF) grant to support his research project titled "Genetic polymorphisms in soluble epoxide hydrolase and outcome after aneurysmal subarachnoid hemorrhage: The role of the epoxyeicosatrienoic acids".

This is a follow up study on Ross's collaborations with Dr. Justin Cetas (Neurosurgery) and Dominic Siler (APOM) recently published in Journal of Neurosurgery and Neurocritical Care. Specifically, Ross previously found that variations in the PEHX2 gene, which codes for an lipid-metabolizing enzyme called soluble epoxide hydrolase, are linked to outcome from hemorrhagic stroke. Ross's new MRF grant will support studies aimed at investigating the mechanism by which these genetic variations (polymorphisms) influence outcome (phenotype). For a resident to be so productive during his clinical training is very impressive and says a lot about his hard work and determination. Congratulations to Ross.

Below are the citations for Ross's recent publications:

Martini RP, Ward J, Siler DA, Eastman JM, Nelson JW, Borkar RN, Alkayed NJ, Dogan A, Cetas JS.

Genetic variation in soluble epoxide hydrolase: association with outcome after aneurysmal subarachnoid hemorrhage. J Neurosurg. 2014 Sep 12:1-8.

Siler DA, Martini RP, Ward JP, Nelson JW, Borkar RN, Zuloaga KL, Liu JJ, Fairbanks SL, Raskin JS, Anderson VC, Dogan A, Wang RK, Alkayed NJ, Cetas JS.

Protective Role of P450 Epoxyeicosanoids in Subarachnoid Hemorrhage. Neurocrit Care.

Nabil Alkayed
Professor and Vice Chair for Research
Department of Anesthesiology & Perioperative Medicine
Oregon Health & Science University