The department offers a unique environment for research and training that combines Systems Physiology with Chemical Biology in a synergistic and highly collaborative atmosphere. Learn more
WelcomeThe Department of Physiology & Pharmacology emphasizes a chemical biology approach to the study of systems physiology. The distinctive mind-set of our faculty can be summed up as a desire to study cellular and molecular events in the context of the whole animal. To do this we have created a research environment in which physiologists and chemical biologists team up to create new chemical tools for probing specific signaling pathways and mechanisms in whole animal models. We believe that connecting systems physiology with cutting edge chemical biology is a powerful way to distinguish the roles of multiple inter-connected processes in vivo and is key to developing new therapeutics in the 21st century. We encourage you to explore these pages – our faculty, graduate programs and our research.
Featured: Duvoisin Lab
The objectives of the laboratory are to study the structure, distribution, and function of G protein-coupled metabotropic glutamate receptors (mGluRs). Because mGluRs modulate, as opposed to mediate, synaptic transmission, compounds acting on mGluRs are being investigated as therapies and are in clinical trials for neurological and psychiatric diseases such as central pain, drug addiction, excitotoxic neuronal injury following stroke, Parkinson's disease, Alzheimer's disease, anxiety and schizophrenia. Learn more
TTBD Innovator Spotlight: Xiangshu Xiao, PhD
Xiangshu Xiao, Ph.D., associate professor of physiology and pharmacology. In his two main cancer-related projects, Dr. Xiao has developed first-in-class compounds that show significant anti-cancer effects in various preclinical cancer models.