OHSU

Parasitology

Malaria, leishmaniasis, and trypanosomiasis are parasitic diseases that affect millions of individuals worldwide and are major public health concerns. Understanding the basic biology of these parasites is critical for developing methods to control disease.Molecular Parasitologists at the MMI employ a synthesis of molecular biology, biochemistry, genetics, cell biology, and pharmacology to investigate the requirements for parasite survival while inside their hosts.Current research is focused on: understanding the mechanisms of resistance to current anti-parasitic drugs, elucidating the function of membrane transporters required for the uptake of Glucose and Purines as key nutrients essential for survival inside the mammalian host cell, and the discovery of new compounds that can be effective used to combat disease.