PubMed Search

Selected Publications

Diphenylether-Modified 1,2-Diamines with Improved Drug Properties for Development against Mycobacterium tuberculosis.
Foss, M.H., Pou, S., Davidson, P.M., Dunaj, J.L., Winter, R.W., Pou, S., et al. (2016). ACS Infect Dis acsinfecdis.6b00052.

Structural basis for the regulation of the MmpL transporters of Mycobacterium tuberculosis.
Delmar, J.A. Chou, T-H, Wright, C.C., Licon,, M.H., Doh, J.K., Radhakrishnan, A., Kumar, N., Lei, H-T., Bolla, J.R., Rajashankar, K.R., Su, C-C., Purdy, G.E. and E. W. Yu. 2015. J. Biol. Chem. 290: 28559–28574. PMID 26396194 PMC4653710.

Crystal structure of the Mycobacterium tuberculosis transcriptional regulator Rv0302.
Chou, T-H, Delmar, J.A. Wright, C.C., Radhakrishnan, A., Kumar, N., Lei, H-T., Bolla, J.R., Rajashankar, K.R., Su, C-C., Purdy, G.E. and E. W. Yu. 2015. Protein Science. 24: 1942–1955. PMID 26362239

Confinement-Induced Drug-Tolerance in Mycobacteria Mediated by an Efflux Mechanism.
Luthuli, B.B., G.E. Purdy and F.K. Balagadde. 2015. PLOS ONE 10(8):e0136231. PMID 26295942 PMC4546595

Crystal Structure of the transcriptional regulator Rv0678 of Mycobacterium tuberculosis.
Radhakrishnan, A., N. Kumar, C. Wright, T-H Chou, J.R. Bolla, C-C. Su, K.R. Rajashankar, L. Messerle, G.E. Purdy, and E.W. Yu. J. Biol. Chem. 289(23):16526-16540. PMID: 24737322

The MmpL11 transporter contributes to mycobacterial cell wall biosynthesis and biofilm formation in M. smegmatis. 
Pacheco, S.A., F.F. Hsu, K.M. Powers, and G.E. Purdy. 2013. J. Biol. Chem. 288:24213-24222. PMID 238369904.

Characterization of mycobacterial triacylglycerols and the unusual monomeromycolyl diacylglycerols from Mycobacterium smegmatis biofilms by linear ion-trap multiple-stage and high-resolution mass spectrometry with electrospray ionization.
Purdy, G.E., Pacheco, S.A., Turk, J., and F.F. Hsu. 2013. Anal. Bioanal. Chem. 405(23), 7415–26. PMID: 23852148

Autophagic killing effects against Mycobacterium tuberculosis by alveolar macrophages from young and aged Rhesus macaque.
Pacheco, S.A., Powers, K.M., Engelmann, Messaoudi, I. and G.E. Purdy. 2013. PLoS ONE 8(6): e66985. doi:10.1371/journal.pone.0066985. PMID 23825603

Structural and functional characterization of mycobactericidal ubiquitin-derived peptides in model and bacterial membranes.
Foss, M.H., Powers, K. M., and G.E. Purdy. 2012. Biochemistry, 51(49):9922-9. PMID:23173767 PMC3567233 

Structural Elucidation of Glycopeptidolipid of Mycobacterium smegmatis by High Resolution Multiple-stage Linear Ion-trap Mass Spectrometry with Electrospray Ionization.
Hsu, F.F., Pacheco, S., Turk, J. and G. Purdy. 2012. J Mass Spectrom. 47(10):1269-81. PMID: 23019158 PMC3462375

Escape from the phagosome: the explanation for MHC-I processing of mycobacterial antigens? 
Harriff, M., Purdy, G.E. and D.M. Lewinsohn. 2012. Front. Immun. 3:40. doi: 10.3389/fimmu.2012.00040. PMID: 22566923 PMC3342008