Stephen Moore, PhD
Stephen Moore, PhD, FACMG - Assistant Professor
Oregon Health & Science University
3181 SW Sam Jackson Park Road
Mail Code # MP350
Portland, OR 97239
Office: 503 494-5400
Fax: 503 494-6104
BIODr. Moore is an Assistant Professor in the Department of Molecular and Medical Genetics, and is the Assistant Director of the Clinical Cytogenetics Laboratory and of the Molecular Diagnostics Laboratory. He is ABMG board-certified in both Clinical Cytogenetics and Clinical Molecular Genetics. He earned a BSc from Washington State University, an MSc from California State University and a PhD in Environmental Toxicology from the University of California. He then did fellowships at the Medical Research Council Radiation and Genome Stability Unit in Oxford, City of Hope (Duarte, CA), Cedars-Sinai/UCLA, and OHSU. Presently, his laboratory interests encompass new test development, including chromosomal microarray analysis for congenital disorders, prenatal diagnostics and cancer, and the development of next generation sequencing panels and exon-specific copy number arrays for rare genetic disorders and cancer; the overall goal of these efforts being the development of genomic tools to guide personalized medicine.
Severe cleidocranial dysplasia and hypophosphatasia in a child with microdeletion of the C-terminal region of RUNX2. El-Gharbawy AH, Peeden JN Jr, Lachman RS, Graham JM Jr, Moore SR, Rimoin DL. Am J Med Genet A. 2010; 152A(1):169-174.
Single nucleotide polymorphism genomic arrays analysis of t(8;21) acute myeloid leukemia cells. Akagi T, Shih LY, Ogawa S, Gerss J, Moore SR, Schreck R, Kawamata N, Liang DC, Sanada M, Nannya Y, Deneberg S, Zachariadis V, Nordgren A, Song JH, Dugas M, Lehmann S, Koeffler HP. Haematologica. 2009 Sep;94(9):1301-6.
Detection of copy number alterations in metastatic melanoma by a DNA fluorescence in situ hybridization probe panel and array comparative genomic hybridization: a southwest oncology group study (S9431). Moore SR, Persons DL, Sosman JA, Bobadilla D, Bedell V, Smith DD, Wolman SR, Tuthill RJ, Moon J, Sondak VK, Slovak ML. Clin Cancer Res. 2008 May 15;14(10):2927-35.
Chronic phase of ETV6-ABL1 positive CML responds to imatinib. Kawamata N, Dashti A, Lu D, Miller B, Koeffler HP, Schreck R, Moore S, Ogawa S. Genes Chromosomes Cancer. 2008 Oct;47(10):919-21.
Challenges in array comparative genomic hybridization for the analysis of cancer samples. Nowak NJ, Miecznikowski J, Moore SR, Gaile D, Bobadilla D, Smith DD, Kernstine K, Forman SJ, Mhawech-Fauceglia P, Reid M, Stoler D, Loree T, Rigual N, Sullivan M, Weiss LM, Hicks D, Slovak ML. Genet Med. 2007 Sep;9(9):585-95.