Primary Faculty

Andrew Adey, Ph.D.

Andrew Adey

Assistant Professor

adey@ohsu.edu

I plan to continue my focus on the development and implementation of novel strategies to investigate the epigenome with high precision. This includes single cell approaches to disambiguate epigenetic and transcriptional heterogeneity within populations of cells which is typically obscured by bulk preparation methods. 
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Mushui Dai, M.D., Ph.D.

Mushi Dai

Associate Professor

daim@ohsu.edu

Our broad research interest is to understand the biological function and molecular mechanisms of the p53 tumor suppression and c-Myc oncogenic pathways, thereby providing a possible means to manipulate p53 and c-Myc function in cancer cells.
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Anna Dennis, M.S., C.G.C.

Anna Dennis

Instructor

dennisa@ohsu.edu

The field of medical genetics is blossoming with rapid advances in technology and clinical knowledge. I feel privileged to make this information accessible to our patients and their families, and to provide the support that meets each family's unique needs.
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Melanie Gillingham, Ph.D., R.D.

Melanie Gillingham

Associate Professor

gillingm@ohsu.edu

Our current work is focused on the treatment of rare disorders in the FAO pathway. Our future goal is to learn from these disorders about the role of fatty acid oxidation in body weight regulation and the development of insulin resistance.
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Kelly Hamman, M.S., C.G.C.

Kelly Hamman

Instructor

hammank@ohsu.edu

Kelly developed a special interest in genetics during her undergraduate studies. Upon graduation, she moved to Portland and worked in a research laboratory investigating gene therapy for inborn errors of metabolism. 
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Cary Harding, M.D.

Cary Harding

Professor

hardingc@ohsu.edu

Inborn errors of metabolism (IEM) affect as many as 1:1500 people with age of onset varying from birth to adulthood.  For many of these disorders, contemporary medical therapy is less than satisfactory. 
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Susan Hayflick, M.D.

Susan Hayflick

Professor and Chair

hayflick@ohsu.edu

Brain iron accumulates in many human neurodegenerative disorders, including Parkinson disease, Alzheimer disease, multiple sclerosis, and HIV encephalopathy. To investigate brain iron dyshomeostasis, we study a group of rare, single gene disorders, called Neurodegeneration with Brain Iron Accumulation (NBIA).
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Kory Keller, M.S., C.G.C.

Kory Keller

Assistant Professor

kellerko@ohsu.edu

Mrs. Keller specializes in pediatric genetic counseling, working on a team with clinical geneticists, to provide diagnostic evaluations and care for children known or suspected of having a genetic disease.
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David Koeller, M.D.

David Koeller

Professor

koellerd@ohsu.edu

Dr. Koeller specializes in inherited (genetic) disorders of metabolism. He is the Director of the OHSU Metabolic Clinic, and Chief of the Division of Metabolism in the Department of Pediatrics.
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Karen Kovak, M.S., C.G.C.

Karen Kovak

Assistant Professor

kovakk@ohsu.edu

Ms. Kovak has been providing genetic counseling services at OHSU for over 30 years, in many areas of specialty.  She has a special interest in Huntington disease, and facilitates a support group for this condition as well as seeing individuals and families with HD at OHSU. 
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Jessica Kushner, M.S., C.G.C.

Jessica Kushner

Instructor

kushnerj@ohsu.edu

Genetic counselors are masters level health care professionals trained to provide information and support to people who have, or may be at risk for, genetic disorders. As part of the OHSU clinical genetics team, Ms. Kushner provides genetic counseling services to children and adult patients with a wide variety of genetic conditions.
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R. Michael Liskay, Ph.D.

Mike Liskay

Professor

liskaym@ohsu.edu

We use yeast and mice to study DNA mismatch repair (MMR), which corrects mismatches and senses DNA damage. MMR gene mutations increase spontaneous mutation and predispose to hereditary and sporadic cancer.
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Stephen R. Moore, Ph.D., FACMG

Stephen Moore

Assistant Professor

moorest@ohsu.edu

Laboratory interests include chromosomal microarray analysis for congenital disorders, the development of sequencing-based tests and panels for rare genetics disorders, and the development of genomic tools.
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Robb Moses, M.D.

Robb Moses

Professor Emeritus

mosesr@ohsu.edu

Dr. Moses' special areas of interest include Fanconi anemia, DNA repair deficiencies, and gene therapy. He is the former Chair for Molecular & Medical Genetics.
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Hiroyuki Nakai, M.D., Ph.D.

Hiroyuki Nakai

Associate Professor

nakaih@ohsu.edu

The major focuses of our laboratory are the elucidation of the biology of recombinant adeno-associated virus (rAAV) vectors and cellular biology associated with rAAV infection/transduction, and development of new rAAV vector-mediated gene and cell therapies to treat various human diseases.
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Susan Olson, Ph.D.

Susan Olson

Professor

olsonsu@ohsu.edu

Chromosome aberrations contribute significantly to human disease. Close collaboration between our clinical and research cytogenetics laboratories contributes to a better understanding of specific chromosome regions and chromosome abnormalities...
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Brian J. O'Roak, Ph.D.

Brian O'Roak

Assistant Professor

oroak@ohsu.edu

Our lab uses genomic approaches to unlock the genetic basis of neurodevelopmental disorders and related disorders, such as autism and intellectual disability. Our goal is to develop early interventions and biologically based personal therapies that can dramatically improve the lives of individuals affected with these disorders.
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Carolyn Sue Richards, Ph.D., FACMG

Sue Richards

Professor

richarsu@ohsu.edu

The focus of my clinical research laboratory is development of sequence-based testing for rare disorders, development of custom analysis to address copy number variants, design of algorithms using analysis tools for interpretation of sequence variations and translation of these products into clinical practice.
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Jone Sampson, M.D.

Jone Sampson

Clinical Associate Professor

sampsojo@ohsu.edu

Dr. Sampson is a clinical geneticist specializing in cancer genetics. She enjoys working in this field because finding gene mutations in families with an inherited tendency for cancer can help save lives through prevention and early detection.
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Rosalie Sears, Ph.D.

Rosalie Sears

Professor

searsr@ohsu.edu

We are studying cellular signaling pathways involved in the generation of human cancer. In general, disruption of these pathways alters the ability of a cell to control its proliferation as well as the initiation of programmed cell death (apoptosis).
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Paul Spellman, Ph.D.

Paul Spellman

Professor

spellmap@ohsu.edu

I am interested in using genetic, genomic, and proteomic data to understand and model the biology of cancer and to develop methods to effectively deploy therapeutic agents in the age of molecularly guided medicine.
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H. Scott Stadler, Ph.D.

Scott Stadler

Associate Professor

hss@shcc.org

Our research ranges from biochemical identification of the DNA sequences preferred by individual HOX proteins to the development of therapeutics aimed at augmenting deficiencies in target gene expression caused by the loss of HOX protein function.
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Amanda Vinson, Ph.D.

Amanda Vinson

Assistant Professor

vinsona@ohsu.edu

Heart disease has been described as a disease of low-grade "smoldering" inflammation, and my research is aimed at understanding how genes and environmental influences contribute to inflammation in coronary heart disease.
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Jon Zonana, M.D.

Jon Zonana

Professor

zonanaj@ohsu.edu

Dr. Zonana's special interests are in clinical genetics, dysmorphology, molecular genetics and the ectodermal dysplasia. He is author of multiple publications dealing with syndrome delineation and causation.
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