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Change of Seasons

OHSU has many stunning works of art throughout its public areas, but one recent addition comes with its own special tale. "Change of Seasons" is located in the corridor just outside the Department of Molecular and Medical Genetics (MMG) on the fourth floor of Richard Jones Hall. It's an acrylic painting by Jennifer Kapnek. Read the full story on the SOM Research Voice Blog.

Calling Dr. Nelson

A huge congratulations is due to Jonathan Nelson, Ph.D. for the successful defense of his thesis entitled, Disruption of Soluble Epoxide Hydrolase Dimerization as a Novel Therapeutic Target for Stroke. Dr. Nelson has been featured in an article in The Daily News (The Lower Columbia) regarding his ground breaking research. Read it here.

MMG Alumnus Recognized

Phouc T. Tran, M.D., Ph.D. has been awarded the Early Career Achievement Award by the School of Medicine. Since graduating with a Ph.D. in Genetics from the Department of Molecular and Medical Genetics in 2001 and an M.D. in 2003, Dr. Tran has continued to excel at every level. He did his residency in radiation oncology at Stanford, where he became chief resident. See the full list of alumni awarded.

ARCS Scholar

MMG Graduate Student, Nichole Owen, was awarded an ARCS Scholarship for third year students. Nichole's research interests include cytogenetics, fanconi, DNA repair processes and disorders, as well as chromosome structure and maintenance. Read more on the ARCS website.

Top Docs

Molecular and Medical Genetics faculty member, Dr. Jone E. Sampson a clinical geneticist specializing in cancer genetics was named among the top 100 doctors by Portland Monthly Magazine. View the full list of top docs.

SOM Paper of the Month

This month's featured paper is from the laboratory of Dr. Cheryl Maslen, and is titled, "An Excess of Deleterious Variants in VEGF-A Pathway Genes in Down-Syndrome-Associated Atrioventricular Septal Defects." For approaching this problem, the team's strategy included a multi-institutional collaboration, careful patient phenotyping, targeted sequencing and careful analytical bioinformatics – a winning combination. Full story

Awards

Dr. Cary Harding's NIH R01 grant 'Novel Therapy for monoamine neurotransmitter deficiency in PKU' was just funded (9/30/12-5/31/16). Dr. Harding states, "We are evaluating the mechanisms that cause and possible novel treatments for central nervous system neurotransmitter deficiency in PKU."

Mushui Dai, M.D., Ph.D., Assistant Professor in the Department of Molecular and Medical Genetics received a grant from the National Cancer Institute. This grant aims at examining the molecular and biochemical mechanism underlying the regulation of the p53-MDM2-MDMX pathway by the deubiquitinating enzyme Otub1, whether Otub1 possesses tumor suppressor function, and whether it is deregulated in human cancers.

Dr. Susan Hayflick, Chair of the Department of Molecular and Medical Genetics is part of an international consortium of scientists that was awarded a 5.2 million euro grant to study NBIA (Neurodegeneration with Brain Iron Accumulation), a rare neurological disorder. Read the TIRCON press release.