MMG encompasses research faculty, clinicians, fellows, and students with diverse research interests surrounding molecular and medical genetics approaches to understanding the basis and treatment of human disease. See who we are
MMG encompasses numerous research faculty, clinicians, fellows, and students with diverse research interests surrounding molecular and medical genetics approaches to understanding the basis and treatment of human disease. Our research includes cancer genetics, molecular genetics, gene therapy technologies, molecular diagnostics, developmental genetics, medical genetics cytogenetics, quantitative trait genetics, biochemical genetics, cell biology and biochemistry. Several laboratories focus on "tumor suppressor" and "oncogene" pathways involved in a variety of common human cancers, with one goal being to capitalize on this knowledge for translational research purposes. One central theme in the program is the utilization of a variety of genetic, molecular and cellular approaches for analyzing normal and disease processes. Learn more
Fatty Acid Oxidation and Retina
One of the complications of LCHAD deficiency is vision loss because of a degeneration of the retina, a part of the eye that is essential for us to see. This degeneration of the retina is called retinopathy and the cause of retinopathy in children with LCHAD is not known. Dr. Melanie Gillingham is currently conducting a study in cells to investigate the cause of LCHAD retinopathy. Help support Dr. Gillingham's research today!
In the News
OHSU neurogeneticist Brian J. O'Roak is one of a select group of researchers in the United States and Canada to be honored with a 2015 Alfred P. Sloan Research Fellowship.
The highly sought-after award honors early-career scientists whose achievements and potential identify them as "rising stars."
"Dr. O'Roak is richly deserving of this recognition," said Dr. Susan Hayflick, professor and chair of the Department of Molecular and Medical Genetics in the OHSU School of Medicine, said in a news release. "He is one of those rare 'bridge' scientists who can lead a high-impact research program that will cut across institutional, basic science and clinical boundaries. At OHSU, O'Roak interacts with clinical investigators at the Child Development and Rehabilitation Center and Doernbecher Children's Hospital, and with leading neuroscience and human genetics researchers. This is an ideal environment for him to make precision medicine in neurodevelopmental disorders a reality." Click here to read the full article from the Oregonian.