Graduate Program Curriculum

Department of Molecular and Medical Genetics graduate program is designed to offer training in the area of genetics. The program offers a range of training opportunities in molecular, cellular, developmental and human genetics. The areas of faculty research include molecular genetics, molecular biology of gene regulation, somatic cell genetics, developmental genetics, medical genetics, cytogenetics, molecular cytogenetics, population genetics, biochemical genetics, cell biology and biochemistry. Some laboratories are focusing on processes such as DNA repair mechanisms at both the basic understanding level and in relation to human disease. Others are involved in positional cloning and characterization of human disease genes. Still other labs are working on basic genetic problems such as cell differentiation in, for example, normal and abnormal muscle cells. One theme in the program is a utilization of a variety of genetic, molecular and cellular approaches for analyzing normal and disease processes. Students have the opportunity to receive genetics clinical experience while participating in the Genetics Clinic on an optional basis.  The opportunities for graduate research on a variety of genetic problems is, however, the central feature of the training program.
Molecular and Medical Genetics is a participating department in the Program in Molecular and Cellular Biosciences (PMCB) at Oregon Health & Science University. This program offers a joint admissions process and a standard first-year curriculum for the five participating departments. The purpose of the program is to offer students the flexibility to select first-year research rotations with any of the participating faculty to gain as much information and experience as possible before making the crucial selection of a topic and mentor for dissertation research.
For more detailed information, please see the Molecular and Medical Genetics Handbook.


First Year Curriculum:

PMCB Core Curriculum

Second Year Curriculum:

 Course Name

Course Number



 Eukaryotic Genetics
 MGEN 622
 3  F
 Journal Club
 MGEN 605/606
 1  F, W, Sp
 Departmental Seminar
 MGEN 607A
 1  F, W, Sp
 Departmental Grand Rounds
 MGEN 611
 1  F, W, Sp
 Genetic Basis of Disease
 MGEN 623
 3  Sp

Common Elective Courses:

 Course Name

 Course Number



 Essentials of Molecular and Medical Genetics
 MGEN 610
 2  W
Clinical Experience in Medical Genetics
 MGEN 609
 2  TBA
 Mechanisms of Cancer Journal Club
 MGEN 606
 1  F, W, Sp
 Cardiovascular and Cerebrovascular Journal Club
 MGEN 605C
 1  F, W, Sp
Molecular & Medical Genetics Journal Club
 MGEN 605E     
 1  F, W, Sp

All Courses Offered by MMG

MGEN 601      Research | 1-16 credits

 Schedule: All Terms

MGEN 603      Dissertation (credits TBA)

                         Schedule: Any Term

MGEN 605C   Cerebrovascular and Cardiovascular Journal Club | 1 credit

 Course Director: McCarty

 Schedule: Fall, Winter, Spring | Wednesday | 4:00pm-5:00pm | CHH 13030 

MGEN 605E   Molecular & Medical Genetics Journal Club |1 credit

 Course Director: Moore

 Schedule: Fall, Winter, Spring | Thursday | 10:30-11:30am | RJH 4504

MGEN 606      Mechanisms of Cancer Journal Club |1 credit
                         Course Director: Dai, Lopez, Qian

                         Schedule: Fall, Winter, Spring | Tuesday | 12:00pm-1:00pm | MAC 2136

MGEN 607A   Departmental Seminar Series | 1 credit
                         Course Director: Hayflick
                         Schedule: Fall, Winter, Spring |Wednesday | 4:00pm-5:00pm | Vollum M1441
                         Seminars presented by students, faculty and visiting speakers on contemporary topics

MGEN 609     Clinical Experience in Medical Genetics | 2 credits

                         Course Director: Kovak
                         Schedule: TBA

 Introduction to genetic counseling techniques and exposure to various genetic clinical settings

MGEN 610     Essentials of Molecular and Medical Genetics | 2 credits                        
Course Director: Vinson                         
                        Schedule: Winter | Tuesday/ Thursday | 3:00pm-4:00pm | MAC 2136                        
                        Introduction to the field of Molecular and Medical Genetics. Discussions are led by senior graduate students and PostDocs with
                        support from faculty mentors in roundtable forum.

MGEN 611     Departmental Grand Rounds | 1 credit
                        Course Director: Zonana and Moore
                        Schedule: Fall, Winter, Spring | Thursday | 9:00am-10:00am | MAC 3198

MGEN 615     Cytogenetics Laboratory | (Credits TBD)                       
                        Course Director: Susan Olson                        
                        Schedule: TBA    

MGEN 620     Interviewing and Counseling Techniques for Genetic Counseling | 1 credit
Course Director: Kovak
Schedule: TBD

Covers theoretical and practical aspects of the genetic counseling process.   Topics highlighted are ethical considerations in genetic counseling, psychological aspects of genetic disorders in individuals and families and the responsibilities and limitations of genetic counselors.

MGEN 622     Eukaryotic Genetics |3 credits
                        Course Director: Richards

                        Schedule: Fall |Monday/Wednesday/Friday | 3:00pm-4:00pm | MAC 2136

A team of faculty experts discusses topics including chromosomal basis of inheritance, mechanisms of mutation, epigenetics, DNA repair, oncogenes and tumor repressors, cell cycle, yeast genetics, somatic cell genetics, population genetics, mouse model systems, immunogenetics, biomedical informatics and human genome variation.  Format is reading and conference style.

MGEN 623     Genetic Basis of Human Disease | 3 credits
                        Course Director: Richards
                        Schedule: Spring |Monday/Wednesday/Friday | 3:00pm-4:00pm | MAC 2136

A team of faculty experts discusses topics including chromosomal basis of disease, cancer genetics, disorders of energy metabolism, amino acid disorders, blood coagulation disorders, congenital heart defects, disorders of extracellular matrix, platelet disorders, endocrine disorders and stem cell/gene therapy.  Format is reading, journal club and conference style

MGEN 624     Gene and Cell Therapy| 2 credits
                        Course Directors: Nakai and Harding
                        Schedule: Winter | Monday/Friday | 3:00pm-4:00pm | MAC 2136

The course presents an introductory overview of various gene delivery systems and cell-based approaches; advances in DNA/RNA/peptide delivery, cellular genome engineering and understanding the biology of cells as therapeutics; applications of gene delivery technologies and cell transplantation with a focus on translational research and current issues in gene and cell therapy and regenerative medicine.  The course consists of lectures by experts in the relevant fields in a lecture/paper discussion format.  Students will be required to write an NIH style research proposal on a relevant topic of their choice and expected to have an oral presentation during the course.