This course utilizes a regional approach to the study of the human body, including coverage of the various functional systems (e.g., cardiovascular, musculoskeletal, endocrine, etc.) and how the functions of these systems are orchestrated by the central and peripheral nervous systems. The course consists of basic science lectures (anatomy, embryology), clinical lectures (surgery, radiology, ob-gyn, etc.), and viewing dissected human cadavers (although graduate students will not be performing these dissections). It provides an excellent overview for graduate students interested in whole animal studies or a student interested in acquiring valuable teaching credentials.
CELL 611 Histology: The Structure and Function of Cells in Tissues (4 credits) spring term, alternate years. This course will introduce graduate students to the structure and function of cells in tissues and organs. The course will focus on understanding both the organization and differentiated functions of the major tissues and organs of the body. The major tool to be used in this course will be the light microscope. Students will develop expertise in the histological identification of tissues and organs under the light microscope.
CELL 615 Advanced Topics in Developmental Neuroscience (3 credits) spring term, alternate years. Advanced graduate course designed to provide an overview of the major aspects of nervous system formation, plus more in-depth presentations of specific topics in the field of neural development and differentiation. Emphasis will be on recent insights into the molecular and cellular mechanisms that underlie specific aspects of neural development, including patterning of the early nervous system, neurogenesis, neuronal migration and axonal outgrowth, synaptogenesis and plasticity, cell death, and neural stem cells in regeneration. Readings will be based selected reviews and articles from the current literature. Interactive discussion sections will involve critical analyses of recent research papers..
CELL 616 Cancer Biology (4 credits) spring term, yearly. The course consists of a comprehensive coverage of topics in cancer biology including mechanisms of carcinogenesis, the roles of oncogenes and tumor suppressor genes, molecular targets for novel therapeutic strategies, and an understanding of the pathogenesis of specific cancers such as breast, prostate, gastrointestinal, skin, and blood. Prerequisites: Instructor consent.
CELL 618 Mechanisms of Development (3 credits) Winter term, alternate years. This course offers an advanced and in depth overview of a selected “hot” topic in the field of Cell and Developmental Biology. Topics covered in previous course offerings include noncoding RNAs, asymmetric stem cell division and endocytic regulation of signal transduction. The topic is explored primarily through student- and postdoc-led discussions of the current literature. Each participant contributes to writing a section of a mini-review focused on the topic, with the goal of submitting the review for publication in a peer-reviewed journal. Participants have the option of enrolling in the course for credit or auditing the course with permission. All participants will be expected to contribute to discussion and writing of the mini-review.
CELL 620 Model Systems Biology (3 credits) summer term. This course provides an introduction to the biology and genetics of the major animal model systems as well as laboratory demonstrations of state-of-the-art techniques. Students will gain a solid understanding of how mice, zebrafish, Xenopus, chickens, and flies are used as tools to study key cell and molecular biology problems. This will help students better interpret the results of the many papers coming out each day in major journals. This course should also aid in making informed choices of thesis and qualifying exam topics. Grades will be based on student presentations of current topics and a final exam. Students at all levels are encouraged to participate.
CELL 622 Topics In Transcriptional Regulation (2 credits) fall term, alternate years. Specific topics concerning mechanisms regulating gene expression will be covered. Some topics will focus on the role of particular transcription factor or co-activator families. Other topics will examine the role of transcriptional changes in regulating physiological processes. The course will involve lectures by faculty and interactive discussion of current papers. Students will be required to prepare a written research proposal. Prerequisite: CON 663