Melissa Wong, Ph.D.
Office: RJH 5582 | 503-494-8749
Lab: RJH 5568
Graduate Program Memberships:
American Association for Cancer Research
International Society for Stem Cell Research
American Gastroenterological Association
1987 University of Colorado, Boulder, CO
1994 Bowman Gray School of Medicine/Wake Forest University, Winston-Salem, NC
1995-1998 Post-doctoral fellow, Washington University School of Medicine
1998-2001 Instructor, Washington University School of Medicine
2001-2008 Assistant Professor, OHSU
2008-present Associate Professor, OHSU
2013-present Vice Chair, Cell & Developmental Biology
Bone marrow-derived cells fuse with normal and transformed intestinal progenitor cells. Rizvi AZ, Swain JS, Bailey AS, Davies PS, Decker AD, Willenbring H, Grompe M, Fleming WH, and Wong MH.Proc. Natl. Acad. Sci. USA, 2006 103:6321-5.
Inflammation and proliferation act together to mediate intestinal cell fusion. Davies PS, Powell AE, and Wong MH.PLOS One, 2009 4:e6530.
Lentiviral mediated transgene expression can potentiate intestinal mesenchymal-epithelial signaling. Dismuke AD, Kohn AD, Moon RT, and Wong MH.Biologic Procedures Online, 2009 Jul 14.
Characterization of the intestinal cancer stem cell marker CD166 in the human and mouse gastrointestinal tract. Levin TG, Powell AE, Davies PS, Silk AD, Dismuke AD, Anderson EC, Swain JR, and Wong MH. Gastroenterology, 2010 139:2072-2082.
Fusion between Intestinal epithelial cells and Macrophages in a cancer context results in nuclear reprogramming. Powell AE, Davies PS, Anderson EA, Silk AD, Pelz C, Impey S and Wong MH.Cancer Research, 2011 71:1497-1505.
Fusion between hematopoietic and epithelial cells in adult human intestine. Silk AD, Gast CE, Davies PS, Fakhari FD, Vanderbeek GE, Mori M, and Wong MH. PlosONE 2013