OHSU

New Faculty Recruitments

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Sudarshan Anand, Ph.D.

Assistant Professor (CDB Primary Faculty)
Lab/Office: RJH 5
Research Interests
CV

 

 

Selected Publications:

A brief primer on microRNAs and their roles in angiogenesis. Anand S. Vasc Cell. 2013 Jan 16;5(1):2. doi: 10.1186/2045-824X-5-2. Download Paper

Emerging Role of Micro-RNAs in the Regulation of Angiogenesis. Anand S, Cheresh DA. Genes Cancer. 2011 Dec;2(12):1134-8. doi: 10.1177/1947601911423032. Download Paper

MicroRNA-132-mediated loss of p120RasGAP activates the endothelium to facilitate pathological angiogenesis. Anand S, Majeti BK, Acevedo LM, Murphy EA, Mukthavaram R, Scheppke L, Huang M, Shields DJ, Lindquist JN, Lapinski PE, King PD, Weis SM, Cheresh DA. Nat Med. 2010 Aug;16(8):909-14. doi: 10.1038/nm.2186. Download Paper


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Evan Lind, Ph.D.

Assistant Professor (MMI Primary Faculty, CDB Joint Appointment)
Lab/Office: RJH 6
Research Interests
CV

 

 

 

Selected Publications:

  • IDH1(R132H) mutation increases murine haematopoietic progenitors and alters epigenetics. Sasaki M, Knobbe CB, Munger JC, Lind EF, Brenner D, Brüstle A, Harris IS, Holmes R, Wakeham A, Haight J, You-Ten A, Li WY, Schalm S, Su SM, Virtanen C, Reifenberger G, Ohashi PS, Barber DL, Figueroa ME, Melnick A, Zúñiga-Pflücker JC, Mak TW. Nature. 2012 Aug 30;488(7413):656-9. doi: 10.1038/nature11323. Download paper.
  • Dendritic cells require the NF-kappaB2 pathway for cross-presentation of soluble antigens.
    Lind EF, Ahonen CL, Wasiuk A, Kosaka Y, Becher B, Bennett KA, Noelle RJ. J Immunol. 2008 Jul 1;181(1):354-63. Download Paper.
  • Mapping precursor movement through the postnatal thymus reveals specific microenvironments supporting defined stages of early lymphoid development.
    Lind EF, Prockop SE, Porritt HE, Petrie HT. J Exp Med. 2001 Jul 16;194(2):127-34. Download Paper.
  • Micro-RNA 155 is required for optimal CD8+ T cell responses to acute viral and intracellular bacterial challenges. Lind EF, Elford AR, Ohashi PS. J Immunol. 2013 Feb 1;190(3):1210-6. doi: 10.4049/jimmunol.1202700. Epub 2012 Dec 28. Download Paper.

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Amanda Lund, Ph.D.

Assistant Professor (CDB Primary Faculty, MMI & OCSSB Joint Appointments)
Lab/Office: RJH 6
Research Interests

 

 

 

Selected Publications:

  • The natural and engineered 3D microenvironment as a regulatory cue during stem cell fate determination. Lund AW, Yener B, Stegemann JP, Plopper GE. Tissue Eng Part B Rev. 2009 Sep;15(3):371-80. doi: 10.1089/ten.TEB.2009.0270. Download Paper.
  • Lymphatic and interstitial flow in the tumour microenvironment: linking mechanobiology with immunity. Swartz MA, Lund AW. Nat Rev Cancer. 2012 Feb 24;12(3):210-9. doi: 10.1038/nrc3186. Download Paper.
  • VEGF-C promotes immune tolerance in B16 melanomas and cross-presentation of tumor antigen by lymph node lymphatics. Lund AW, Duraes FV, Hirosue S, Raghavan VR, Nembrini C, Thomas SN, Issa A, Hugues S, Swartz MA. Cell Rep. 2012 Mar 29;1(3):191-9. doi: 10.1016/j.celrep.2012.01.005. Epub 2012 Feb 23. Download Paper.

nolz

 

Jeffrey Nolz, Ph.D.

Assistant Professor (MMI Primary Faculty, CDB Joint Appointment)
Lab/Office: RJH 6
Research Interests
CV

 

 

 

Selected Publications:

  • Strategies and implications for prime-boost vaccination to generate memory CD8 T cells.
    Nolz JC, Harty JT. Adv Exp Med Biol. 2011;780:69-83. doi: 10.1007/978-1-4419-5632-3_7. Download Paper.
  • Immunologic considerations for generating memory CD8 T cells through vaccination.
    Butler NS, Nolz JC, Harty JT. Cell Microbiol. 2011 Jul;13(7):925-33. doi: 10.1111/j.1462-5822.2011.01594.x. Epub 2011 Apr 28. Download Paper.
  • Protective capacity of memory CD8+ T cells is dictated by antigen exposure history and nature of the infection. Nolz JC, Harty JT. Immunity. 2011 May 27;34(5):781-93. doi: 10.1016/j.immuni.2011.03.020. Epub 2011 May 5. Download Paper.
  • Naive, effector and memory CD8 T-cell trafficking: parallels and distinctions.
    Nolz JC, Starbeck-Miller GR, Harty JT. Immunotherapy. 2011 Oct;3(10):1223-33. doi: 10.2217/imt.11.100. Download Paper.
  • Division-linked generation of death-intermediates regulates the numerical stability of memory CD8 T cells. Nolz JC, Rai D, Badovinac VP, Harty JT. Proc Natl Acad Sci U S A. 2012 Apr 17;109(16):6199-204. doi: 10.1073/pnas.1118868109. Epub 2012 Apr 2. Download Paper.

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Pepper Schedin, Ph.D.

Professor (CDB Primary Faculty)
Lab/Office RJH 5
Research Interests
CV

 

 

Selected Publications


Postpartum diagnosis demonstrates a high risk for metastasis and merits an expanded definition of pregnancy-associated breast cancer
. Callihan EB, Gao D, Jindal S, Lyons TR, Manthey E, Edgerton S, Urquhart A, Schedin P, Borges VF. Breast Cancer Res Treat. 2013 Apr;138(2):549-59. doi: 10.1007/s10549-013-2437-x. Epub 2013 Feb 22. Download

Developmental windows of breast cancer risk provide opportunities for targeted chemoprevention. Martinson HA, Lyons TR, Giles ED, Borges VF, Schedin P. Exp Cell Res. 2013 May 9. pii: S0014-4827(13)00189-4. doi: 10.1016/j.yexcr.2013.04.018. Download

Collagen architecture in pregnancy-induced protection from breast cancer.
Maller O, Hansen KC, Lyons TR, Acerbi I, Weaver VM, Prekeris R, Tan AC, Schedin P. J Cell Sci. 2013 Sep 15;126(Pt 18):4108-10. doi: 10.1242/jcs.121590. Epub 2013 Jul 10. Download

Postpartum mammary gland involution drives progression of ductal carcinoma in situ through collagen and COX-2. Lyons TR, O'Brien J, Borges VF, Conklin MW, Keely PJ, Eliceiri KW, Marusyk A, Tan AC, Schedin P. Nat Med. 2011 Aug 7;17(9):1109-15. doi: 10.1038/nm.2416. Download

Macrophages are crucial for epithelial cell death and adipocyte repopulation during mammary gland involution
. O'Brien J, Martinson H, Durand-Rougely C, Schedin P. Development. 2012 Jan;139(2):269-75. doi: 10.1242/dev.071696. Epub 2011 Nov 30. Download

Alternatively activated macrophages and collagen remodeling characterize the postpartum involuting mammary gland across species. O'Brien J, Lyons T, Monks J, Lucia MS, Wilson RS, Hines L, Man YG, Borges V, Schedin P. Am J Pathol. 2010 Mar;176(3):1241-55. doi: 10.2353/ajpath.2010.090735. Epub 2010 Jan 28. Download


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Kunyoo Shin, Ph.D.

Assistant Professor (CDB Primary Faculty)
Lab/Office: RJH 5
Research Interests
CV
 


 

Selected Publications:


Cellular Origin of Bladder Neoplasia and Tissue Dynamics of its Progression to Invasive Carcinoma. Shin K*, Lim A, Odegaard JI, Honeycutt JD, Kawano S, Hsieh MH, Beachy PA*. Nat. Cell Biol. 2014 May;16(5):469-78. *Co-corresponding authors. Download paper

Hedgehog/Wnt Feedback Supports Regenerative Proliferation of Bladder Stem Cell. Shin K*, Lee J, Guo N, Kim J, Lim A, Qu L, Mysorekar IU, Beachy PA*. Nature. 2011 Apr 7;472(7341):110-4. * Co-corresponding authors. Recommended by Faculty of 1000. Download Paper

Mechanosensitive Hair Cell-Like Cells from Embryonic and Induced Pluripotent Stem Cells. Oshima K, Shin K, Peng AW, Ricci AJ, Heller S. Cell. 2010 May 14;141(4):704-16. Download Paper

PATJ Regulates Directional migration of Mammalian Epithelial Cells. Shin K, Wang Q and Margolis B. EMBO Rep. 2007 Feb;8(2):158-64. Download Paper

Tight Junction and Cell Polarity. Shin K, Vanessa CF and Margolis B. Annu Rev Cell Dev Biol. 2006 Nov; 22:207-35. Download Paper

PATJ Regulates Tight Junction Formation and Polarity in Mammalian Epithelial Cells. Shin K, Straight SW and Margolis B. J Cell Biol. 2005 Feb 28;168(5):705-11. Download Paper

Loss of PALS1 Expression Leads to Tight Junction and Polarity Defects. Straight SW, Shin K, Fogg VC, Fan S, Liu CJ, Roh M, Margolis B. Mol Biol Cell. 2004 Apr;15(4):1981-90. Download Paper