BME 607 Biomedical Engineering Seminar

Credit(s): 0          Terms: Fall, Winter, Spring
(BME Students: 3 terms required)
This seminar course will feature presentations and discussions on topics in biomedical engineering that exemplify the wide range of applications of biomedical engineering to science and medicine. The goals are to provide the students with an overview of the diverse opportunities for research and application, to foster development of critical analysis and thinking, and to stimulate creative problem solving and research planning.


BME 622 Biomed Opt I: Tissue Optics

Credit(s): 3
Light propagation in tissue: This course treats light transport in scattering and absorbing media such as biological tissue. Light transport is modeled using a variety of theories and computational techniques, including Monte Carlo simulations and approximate solutions of the radiative transport equation. Steady-state and time-dependent problems are treated. Spectroscopy and fluorescence measurements are introduced. Optical imaging techniques are presented. Students learn the basics required for design of optical devices for therapy and diagnostics.


BME 623 Biomed Opt II: Laser Tissue Interactions

Credit(s): 3          Term: Winter 2014
The course treats the immediate physical processes that accompany the absorption of light by biological tissues, including photochemical reactions, heating and tissue coagulation, vaporization, creation of plasmas, and production of stress waves in tissue. Such processes are modeled using finite-difference techniques. Applications in medicine and biology are discussed.
Prerequisite: BME 622 Biomedical Optics I, or permission of instructor.


BME 640 Fluid Mechanics/Biotransport

Credit(s): 3          Term: Spring 2014
This course will introduce basic concepts of fluid mechanics and convective mass transport. It will start with a derivation of mass, momentum and energy conservation equations for fluid flows. The importance of non-dimensional parameters such as Reynolds number and the Womersley parameter will be extensively discussed, and non-dimensional equations will be derived. Other topics will include Bernouilli's equation, low and high Reynolds number flows, oscillatory flows, interactions of fluid flows with tissue and boundary layers. The final part of the course will cover the derivation and use of mass transport equations in fluid flows. Examples from different areas of biomechanics will be discussed throughout the course.

As part of this course, each student will be asked to work on a project. Students will be encouraged to choose project themes from their own research areas or interests. Access to a finite element commercial package will be available for interested students. Through the project, students will be exposed to current analytical and computational methodologies to analyze fluid flow dynamics.


BME 641 Mechanical Properties of Tissues I

Credit(s): 3
This course introduces the application of continuum mechanics to biological tissues. A rigorous derivation of stress and strain tensors, the theory of elasticity and the theory of viscoelasticity are presented. The bulk of the course focuses on the development of pseudo-strain energy density functions to describe the hyperelastic behavior of biological tissues. Suggested Prerequisites: Mathematics through differential equations, some familiarity with linear algebra and matrix manipulations, MATLAB programming skills.


BME 680 Signals and Linear Systems

Credit(s): 3
This course provides a comprehensive treatment of signals, linear systems, and their interactions at a rigorous introductory level. The essential mathematical tools for analyzing continuous- and discrete-time signals, such as Fourier, Laplace, and Z-Transforms, are reviewed. Analytical techniques for studying linear systems using convolution and state-space representations are introduced. The course will develop a general framework for time-varying linear systems, however, special emphasis will be placed on linear time-invariant systems. The concepts of canonical realizations, equivalent systems, canonical transformations and decompositions, solutions of state equations, Lyapunov stability, controllability, observability will be introduced. State feedback and observer design and the Kalman filter will be visited.


BME 682 Nature & Analysis of Bio Signaling

Credit(s): 3
This course will explore, from an engineering perspective, the physiological origins and characteristics of signals that are used medically to monitor patient functions and scientifically to study biological systems. The signals will include arterial and venous blood pressures, electrocardiogram, electroencephalogram, electromyogram, peripheral nerve action potentials and pulse oximetry. Topics will include physiological signal generators, instrumentation, signal processing, and modeling of biological systems. The format will include lectures, lab demonstrations and visits to clinical facilities.
Prerequisite: EE 680


BME 690 Topics in Nanomedicine

Credit(s): 3          Term: Spring 2014
Nanomedicine involves the development and application of materials and devices to study biological processes and to treat disease at the level of single molecules and atoms.We will introduce basic principles underlying nanomedicine and review how nanomedicine is redefining clinical research in areas such as diagnostic imaging agents, nanomaterial-based drug delivery, and nanoscale proteomics.Specific attention will be directed to disease processes including: cancer, kidney, and neurodegenerative