Cardiovascular Computational Mechanics Research
Mechanical forces play a significant role in biological systems and processes. For example, shear forces from blood flow affect attachment and peeling of cells and micro-bubbles (used as contrast agents for ultrasound imaging), hemodynamic forces regulate cardiovascular remodeling and heart development and affect thrombus growth, and surface tension forces determine the spread and transport of pulmonary surfactant inside the lungs.
Research projects at the Rugonyi Lab aim to understand the role of biomechanical forces on heart development, mural thrombogenesis and pulmonary surfactant function. To this end we use a combination of physiological data, imaging, mathematical modeling and computational simulation. Our ultimate goal is to understand the biological mechanisms by which mechanical forces affect biological processes.
Read more about our individual research projects:
Rugonyi Lab Research News
The Rugonyi Lab's work on Cardiac Development was featured in the July 2013 issue of International Innovation, an international publication dissemination resource. International Innovation, accessible through Research Media, is a not just a publication for scientists, but the wider scientific, technology and research communities, dedicated to promoting discoveries and innovations in research and technology globally.