Publications

2015

  • Chen, M; Peters, A; Huang, T; Nan, XL*. Ras dimer formation as a new signaling mechanism and potential cancer therapeutic target. mini-Review in Medicinal Chemistry (Accepted to a special issue on Ras biology, structure, and drug development).
  • Nan, XL*; Meyer-Tamguney, T ; Collisson, EA ; Lin, LJ ; Pitt, C ; Galeas, J ; Lewis, S ; Gray, JW*; McCormick, F*; Chu, S*. Ras-GTP dimers activate the mitogen-activated protein kinase (MAPK) pathway. PNAS, 112(26), 7996 (2015). 
    Also view the commentary on our article, 'Seeing is believing - Ras dimers visualized in live cells' by Drs. Mark Philips and Channing Der.
  • Nickerson, A; Huang, T; Lin, LJ; Nan, XL*. Photoactivated localization microscopy with bimolecular fluorescence complementation (BiFC-PALM). J. Vis. Exp. (In press).
  • Baker-Groberg, S; Phillips, KG; Healy, LD; Itakura, A; Porter, JE; Newton, PK; Nan, XL; McCarty, OJT. Critical behavior of subcellular density organization during neutrophil activation and migration. Cellular and Molecular Bioengineering (In press).
  • Peters, A; Nickerson, A; Lin, LJ; Nan, XL*. Quantitative superresolution microscopy for cancer biology and medicine. In Super-resolution Imaging in Medicine and Biology. Edited by Alberto Diaspro and Marc AMJ van Zandvoort. Taylor & Francis Books, Inc. (submitted).

2014

  • Nickerson, A; Huang, T; Lin, LJ; Nan, XL*. Photoactivated localization microscopy with bimolecular fluorescence complementation (BiFC-PALM) for nanoscale imaging of protein-protein interactions in cells. PLoS ONE. 9(6), e100589 (2014). View online

2013

  • Nan, XL*; Collisson, EA; Kuo, SYL ; Huang, J; Meyer, TM; Liphardt, J; McCormick, F; Gray, JW; Chu, S. Quantitative single-molecule superresolution imaging allows visualization of Raf dimerization and signaling. PNAS, 110(46), 18519 (2013). Highlighted in Sci. Transl Med: 5, 211ec187 (2013). View online
  • Itakura, A; Aslan, JE; Kusanto, BT; Phillips, KG; Nan, XL; Insall, RH; Chernoff, JC; McCarty, OJT. p21-activated kinase (PAK) regulates cytoskeletal reorganization and directional migration in human neutrophils. PLoS ONE, 8(9), e73063:1 (2013). View online
  • Ying, H; Nan, XL; Sengupta, P; Lippincott-Schwartz, J ; Cang, H. Accelerating 3B single molecule super-resolution microscopy with cloud computing. Nature Methods, 10, 96 (2013). View online

Prior to OHSU