Nathan R. Selden, M.D., Ph.D.
Positions
Campagna Professor of Pediatric Neurosurgery
Director Residency Program, Neurological Surgery
Vice-chairman Education, Neurological Surgery
Contact
Department Phone: 503 494-4314; Fax: 503 494-7161; Office: Center for Health & Healing Mail Code: CH8N
Research Areas
pain, pain modulation, analgesia, hyperalgesia, neuromodulation, stem cells
Preceptor Rotation Availability
Dr. Selden is not available for preceptor rotations at this time.
Mentorship Availability
Dr. Selden is not available for mentorship at this time.
Research Interests
Dr. Selden continues a career-long interest in functional neurochemistry. His current work on pain modulatory centers in the amygdala and brainstem is funded by the NIH, the Oregon Child Health Research Center, and the Cameron Foundation. His clinical focus is functional neurosurgery for children, including epilepsy and spasticity. In November 2006, he performed the first implantation of neuronal stem cells in a human patient, as co-Principal Investigator of a trial treating Batten's Disease. He is also interested in clinical evidence regarding spinal dysraphism and is an author of the Pediatric Traumatic Brain Injury Guidelines.
Dr. Selden has served as the Scientific Program Chair and Annual Meeting Chair for the Congress of Neurological Surgeons. He is currently the CNS Secretary. He is a member of the Society of Neurological Surgeons ('Senior Society'), American Society of Pediatric Neurosurgeons, the American Association of Neurological Surgeons, the Western Neurosurgical Society, and the Harvard Aesculapian Society and is a Fellow of the American College of Surgeons, the American Academy of Pediatrics, and the Cambridge Philosophical Society. He has a significant interest in lifelong neurosurgical education, and serves as the Editor of the Self-Assessment in Neurological Surgery (SANS) and on the editorial board of Pediatric Neurosurgery.
For more information, please visit Dr. Selden's Clinical Profile
Education and Training
Nathan Selden was born in Boston, Massachusetts and raised in Oregon, where his father was Vice Chairman of Cardiology at Oregon Health & Science University. He graduated from Exeter and with Distinction from Stanford, winning the Dean's Award for Service, election to Phi Beta Kappa, and the Dinkelspiel Commencement Award. As a British Marshall Scholar, he then spent three years at Cambridge University, completing a Ph.D. in neuroscience and rowing for Jesus College. At Harvard Medical School, he was awarded the John E. Thayer Scholarship and graduated cum laude, in neuroanatomy.
Dr. Selden trained at the University of Michigan under the chairmanship of Dr. Julian Hoff and was introduced to pediatric neurosurgery by Dr. Karin Muraszko. His post-doctoral work on human basal ganglia anatomy was recognized in 1998 by the American Academy of Neurological Surgery, Resident Award. He also served after residency as a clinical fellow in pediatric neurosurgery at Children's Memorial Hospital in Chicago.
Selected Recent Publications
Connolly, E.S., Hoh, B.L., Selden, N.R., Asher, A.L., Kondziolka, D., Boulis, N., and Barker, F.G. (2010) Clipping versus coiling for ruptured intracranial aneurysms: Integrated medical learning at CNS 2007. Neurosurgery 66:19-34.
Oliveria, S.F., Thompson, E.M. and Selden, N.R. (2010) Lumbar lipomyelomeningocele and sacrococcygeal teratoma in two siblings: Support for the dysembryogenic theory of spinal teratoma formation. In press, Journal of Neurosurgery: Pediatrics.
Panczykowski, B.S., Nemecek, N., and Selden, N.R. (2010) Traumatic type III odontoid fracture and severe rotatory subluxation in a 3-year-old child. Journal of Neurosurgery: Pediatrics 5(2):200-203 (with Cover illustration).
Golshani, K.J., Lalwani, K., Delashaw, J.B. and Selden, N.R. (2009) Modified orbitozygomatic craniotomy for radical resection of craniopharyngioma in children. Journal of Neurosurgery: Pediatrics 4(4):345-352 (with Cover illustration).
Scarrow, A.M., Linskey, M., Asher, A.L., Anderson, V.C., and Selden, N.R. (2009) Neurosurgeon transition to retirement: Results of the 2007 CNS Consensus Conference. Neurosurgery 65(2):231-236.
Asher, A.L., Kondziolka, D., and Selden, N.R. (2009) Addressing deficiencies in American healthcare education: A call for informed instructional design. Neurosurgery, 65(2)223-230.
Vogelbaum, M.A., Asher, A.L., Kondziolka, D., Boulis, N.M., Selden, N.R., Hoh, B.L., and Barker, F.G. (2008) Modern treatment of cerebral metastases: Integrated medical learning at CNS 2007, Journal of Neuro-Oncology 93:89-105. DOI 10.1007/s11060-009-9833-4
Sohaey, R., Oh, K., Kennedy, A., Ameli, J., and Selden, N. (2009) Prenatal diagnosis of tethered spinal cord: A pictorial essay. Ultrasound Quarterly, 25(2):83-87.
Nevrekar, D., Abdu, E., and Selden, N.R. (2009) Craniectomy for a bilobed dermoid cyst in the temporal fossa and greater wing of the sphenoid bone: Case report. Pediatric Neurosurgery 45:46-48. DOI: 10.1159/000204902.
Ortiz, J.P., Close, L.N., Heinricher, M.M. and Selden, N.R. (2008) Alpha2-noradrenergic antagonist administration into the central nucleus of the amygdala blocks stress-induced hypoalgesia in awake behaving rats. Neuroscience 157:223-228. 10.1016/j.neuroscience.2008.08.051
Close, L., Cetas, J., Heinricher, M.M. and Selden, N.R. (2009) Purinergic receptor immunoreactivity in the rostral ventromedial medulla. Neuroscience, 158:915-921. 10.1016/j.neuroscience.2008.08.044
Nicholson, N. and Selden, N.R. (2009) Poets, doctors and the rhetoric of money. In press, Neurosurgery, January, 2009.
Hedges, J.R., Newgard, C.D., Veum-Stone, J., Selden, N.R., Adams, A.L., Lenfesty, B., Diggs, B.S., Arthur, M. and Mullins, R.J. (2008) Early Neurosurgical Procedures Enhance Survival in Significant Blunt Head Injury – Observational Analysis Using Propensity Score Adjustment for Procedural Intervention, Journal of Emergency Medicine. doi:10.1016/j.jemermed.2008.07.001
Guillaume, D.J., Huhn, S.L., Selden, N.R., and Steiner, R.D. (2008) Cellular therapy for neurodegenerative disease in children. Part I: Rationale and preclinical studies. Journal of Neurosurgery: Neurosurgery Focus, 24(3&4):E21,1-6. (DOI: 10.3171/FOC/2008/24/3-4/E21)
Selden, N.R.*, Guillaume, D.J., Steiner, R.D., and Huhn, S.L. (2008) Cellular therapy for neurodegenerative disease in children. Part II. Clinical trial design and implementation. Journal of Neurosurgery: Neurosurgery Focus, 24(3&4):E22,1-6. (DOI: 10.3171/FOC/2008/24/3-4/E22).
