The Neuroscience Grad Program provides outstanding training in neuroscience in one of the US’s most livable cities. NGP program strengths include the diversity of research community and career prospects for graduates. Explore NGP research expertise
Welcome to the Vollum Institute/OHSU Neuroscience Graduate Program
Founded in 1992, the Neuroscience Graduate Program at OHSU has 47 predoctoral students and more than 140 faculty in a broad range of subdisciplines. The program is intended for students planning a career in academic or industry research, but we encourage student to explore the career path that matches their ambitions and expertise. The program is particularly strong in cellular neuroscience, neuronal signaling, gene regulation, biophysics of channels and transporters, sensory systems, and neuroendocrinology with increasing strength in developmental neuroscience and disease-oriented neuroscience research. Faculty members are located within research institutes at OHSU including the Vollum Institute, the Oregon National Primate Research Center (ONPRC), Oregon Hearing Research Center, Jungers Center and the Oregon Institute for Occupational Health Sciences; as well as the basic and clinical departments in the OHSU School of Medicine.
Glia perform important immune functions to defend the brain against toxic insults and minimize damage after injury. In the aging brain, it has been proposed that changes in glial immunity may be related to the onset of some neurodegenerative diseases. We used a well-established acute axotomyassay in Drosophila to examine how key features of glial immunity are altered with age. Our studies show that in the aging brain glial engulfment of neurodegenerative material is dysfunctional due to down regulation of the Draper receptor at the protein level, as a result of decreased PI3K92E activity and translation efficiency. Additionally, we demonstrate that aged Drosophila olfactory nerves are delayed in initiating Wallerian degeneration after injury, similar to what has been previously shown in mammals. However, increasing Draper/PI3K92E activity in the aging brain was sufficient to rescue both reduced Draper expression and delayed glial clearance of severed axons after injury. This work highlights reduced glial engulfment activity as an intriguing candidate mechanism for age-related vulnerability to neural damage and disease. Congratulations to Maria Purice on her important publication in Nature Communications!
Antoinette Foster, starting her 3rd year in the Vollum/OHSU Neuroscience Graduate Program, has been awarded a Gilliam Fellowship from the Howard Hughes Medical Institute. The Gilliam Fellowship for Advanced Study program awards a select number of fellowships nationwide to outstanding scientists who are pursuing a PhD in the life sciences and who are committed to increasing diversity among scientists. The 3-year fellowship not only provides financial support, but also the opportunity to attend meetings with HHMI scientists and receive professional development mentoring as part of the program. Antoinette was nominated from OHSU by the directors of the NIH training grant, T32NS007466, "Multidisciplinary Training in Neuroscience" and is pursuing her thesis research in the laboratory of Ben Emery in the Jungers Center. Congratulations, Antoinette!
Congratulations to 2nd year NGP students Nathan Yoder (Gouaux lab) and Will Hendricks (Schnell lab) who received NIH F31 predoctoral fellowships in 2016. They join 12 other current upper level NGP students (above year 2) that have received individual NSF or NIH fellowships, nearly 50 % of those eligible.
Congratulations to NGP students, Reena Clements (photo below) and Christopher Vaaga, on their 2015 LaCroute Neurobiology of Disease Fellowships (formerly known as the OBI Fellowship). Out of 24 applications, these were the two selected by the OBI Research Committee. Congratulations to both of you!
Reena Clements, a 3rd year NGP student in Dr. Kevin Wright’s lab, was selected to participate in the OMSI Science Communication Fellowship Program. As a Fellow, Reena will participate in professional development workshops to hone her skills at communicating science to a general audience. She will also participate in OMSI’s “Meet a Scientist” program, where she will be able to share her research with museum visitors. Reena is very dedicated to science outreach and currently volunteers with middle and high school students through the Brain in the Box and OnTrack programs at OHSU. She is excited for the opportunity to share her passion for science with the broader community as an OMSI Fellow.
Danielle Robinson, a 5th year Neuroscience Graduate Program (NGP)student, has been selected to attend OpenCon 2015 with a full travel scholarship, in Brussels, Belgium this November. Shelley Mason, a postdoctoral researcher in the Department of Cell, Developmental & Cancer Biology and founder of UnpublishableScience.com, was also selected to attend. The travel award is made possible by a grant awarded to the OHSU Library, "Catalyzing a Culture of Open Science", funded by the National Network of Libraries of Medicine, and is part of a year-long project to support scientific communication education and Open Science advocacy.
OpenCon is a small conference that brings scientists together with other academic professionals to discuss issues of Open Access, Open Data, and Open Education. Organized by the Right to Research Coalition, the conference is focused on skills development and facilitating connections with policymakers and Open Science leaders. 2015 speakers include Michael Eisen (UC Berkeley, HHMI) and Patrick Brown (Stanford), co-founders of the Public Library of Science (PLOS).
Danielle first became aware of the Open Access movement through reading Open Access publications like eLife, where NGP Program Director Gary Westbrook is a senior editor. At OpenCon, she will receive mentorship and training in critical communication and technical skills to bring back to OHSU and advance the cause of Open Science in the Pacific Northwest. Danielle is interested in bringing speakers and events to campus to help early career scientists build practical data transparency and data sharing skills, particularly critical in light oft he Fair Access to Science and Technology Research Act (FASTR), which is sponsored by Oregon Senator Ron Wyden and recently received unanimous committee approval. She is also interested in bringing workshops to campus to strengthen computer programming skills to allow researchers to take advantage of the latest open access data analysis and visualization methods.
Danielle is a PhD Candidate in the lab of Fred Robinson (no relation) where she studies the inherited peripheral neuropathy Charcot-Marie-Tooth type 4B2 (CMT4B2). She is an NSF Graduate Research Program Fellow and an ARCS Scholar. She is also a founding member of the OHSU Women in Science Organization, the Science Policy Discussion Group, and the Data Science Interest Group.
An update from Zev Einhorn, Class of 2012.
Hope all is well in lovely Portland. I wanted to give you a brief update. I completed my Ph.D. with Teresa Nicolson in November 2012 and started a postdoc at the University of Pennsylvania. I switched from neuroscience to immuno-oncology for which I proposed to study how macrophages interact with invasive cells in a cancer-like model. I got a competitively funded fellowship grant from NIH, the F32 NRSA. In my third year of the postdoc I'm about to submit my first co-first author paper and expect to have another first author paper submitted by the end of the year.
As you know the landscape for all levels of scientists has shifted and I had the privilege of talking with Dr. Bruce Alberts about how science can be reformed. Despite all the gloom and doom sentiments often expressed there are many opportunities for Ph.D.s and outstanding resources that can be easily found. One of the many clear sighted aspects of my training at OHSU was the requirement to give 2 talks a year. This pushed me to overcome my fear of speaking pretty quickly, at first at the Vollum and then later externally, and by the end I really enjoyed giving talks. As I'm applying for positions, it is essential to showcase that I have interacted with key leaders in my field, and the requirement to give talks is a great starting place. My own choice is to apply for positions as a Medical Science Liaison, or life specialist consultant, as well as scientist positions in Pharma/Biotech. Thanks for all the support over the years. I would be happy to talk with Ph.D.candidates who might want to know more about the versatility of a Ph.D. I have discovered a lot of tools and resources that can help those interested would be happy to share.