List of publications
About
MD/PhD students are involved in a wide variety of research projects across the OHSU campuses. Below are some of the recent journal articles they have written or co-written.
Publications
2011
Adenosine kinase determines the degree of brain injury after ischemic stroke in mice. Shen HY, Lusardi TA, Williams-Karnesky RL, Lan JQ, Poulsen DJ, Boison D. J Cereb Blood Flow Metab. 2011 Mar 23. http://www.ncbi.nlm.nih.gov/pubmed/21427729
N-terminal transmembrane domain of SUR1 controls gating of Kir6.2 by modulating channel sensitivity to PIP2. Pratt EB, Tewson P, Bruederle CE, Skach WR, Shyng SL.Journal of General Physiology. 2011 Feb 14. http://jgp.rupress.org/content/early/2011/02/09/jgp.201010557.long
Pain experienced using two different methods of endometrial biopsy: a randomized controlled trial. Leclair CM, Zia JK, Doom CM, Morgan TK, Edelman AB. Obstet Gynecol. 2011 Mar;117(3):636-41. http://www.ncbi.nlm.nih.gov/pubmed/21343767
Proof of concept: pharmacological preconditioning with a Toll-like receptor agonist protects against cerebrovascular injury in a primate model of stroke. Bahjat FR, Williams-Karnesky RL, Kohama SG, West GA, Doyle KP, Spector MD, Hobbs TR, Stenzel-Poore MP. J Cereb Blood Flow Metab. 2011 Feb 2. [Epub ahead of print] http://www.ncbi.nlm.nih.gov/pubmed/21285967
The cell giveth and the cell taketh away: An overview of Notch pathway activation by endocytic trafficking of ligands and receptors. Pratt EB*, Wentzell JS*, Maxson JE, Courter L, Hazelett D, Christian JL. Acta Histochemica. 2011 May;113(3):248-55. Epub 2010 Feb 1. http://www.ncbi.nlm.nih.gov/pubmed/20122714
2010
Activation of OX40 augments Th17 cytokine expression and antigen-specific uveitis. Zhang Z, Zhong W, Hinrichs D, Wu X, Weinberg A, Hall M, Spencer D, Wegmann K, Rosenbaum JT. Am J Pathol. 2010 Dec;177(6):2912-20. http://www.ncbi.nlm.nih.gov/pubmed/20952591
Arcuate Nucleus Proopiomelanocortin Neurons Mediate the Acute Anorectic Actions of Leukemia Inhibitory Factor via gp130. Grossberg AJ, Scarlett JM, Zhu X, Bowe DD, Batra AK, Braun TP, Marks DL Endocrinology 151: 606–16. 2010 http://endo.endojournals.org/cgi/content/abstract/151/2/606
Conserved proximal promoter elements control repulsive guidance molecule c/hemojuvelin (Hfe2) gene transcription in skeletal muscle. Severyn CJ, Rotwein P. Genomics v96:342–351. 2010 http://www.ncbi.nlm.nih.gov/pubmed/20858542
Cross-presentation of a spread-defective MCMV is sufficient to prime the majority of virus-specific CD8+ T cells. Snyder CM, Allan JE, Bonnett EL, Doom CM, Hill AB. PLoS One. 2010 Mar 12;5(3):e9681 http://www.ncbi.nlm.nih.gov/pubmed/20300633
Deep brain stimulation does not silence neurons in subthalamic nucleus in Parkinson's patients. Carlson JD, Cleary DR, Cetas JS, Heinricher MM, Burchiel KJ. J Neurophysiol. 2010 Feb;103(2):962-7. http://www.ncbi.nlm.nih.gov/pubmed/19955287
Evasion of CD8+ T cells is critical for superinfection by cytomegalovirus.Hansen SG, Powers CJ, Richards R, Ventura AB, Ford JC, Siess D, Axthelm MK, Nelson JA, Jarvis MA, Picker LJ, Früh K. Science. 2010 Apr 2;328(5974):102-6. http://www.ncbi.nlm.nih.gov/pubmed/20360110
Genetic and pharmacologic blockade of central melanocortin signaling attenuates cardiac cachexia in rodent models of heart failure. Scarlett JM, Bowe DD, Zhu X, Batra AK, Grant WF, Marks DL. J Endocrinol. 2010 Jul;206(1):121-30. Epub 2010 Apr 6. http://www.ncbi.nlm.nih.gov/pubmed/20371568
Granulocyte-colony stimulating factor reactivates human cytomegalovirus in a latently infected humanized mouse model. Smith MS, Goldman DC, Bailey AS, Pfaffle DL, Kreklywich CN, Spencer DB, Othieno FA, Streblow DN, Garcia JV, Fleming WH, Nelson JA. Cell Host Microbe. 2010 Sep 16;8(3):284-91. http://www.ncbi.nlm.nih.gov/pubmed/20833379
HGF upregulation contributes to angiogenesis in mice with keratinocyte-specific Smad2 deletion. Hoot KE, Oka M, Han G, Bottinger E, Zhang Q, Wang XJ. J Clin Invest. 2010 Oct 1;120(10):3606-16. doi: 10.1172/JCI43304. http://www.ncbi.nlm.nih.gov/pubmed/20852387
Hypothalamic mechanisms in cachexia. Grossberg AJ, Scarlett JM, Marks DL Physiol Behav 100: 478-89. 2010. Review. http://www.ncbi.nlm.nih.gov/pubmed/20346963
Interactions between copper-binding sites determine the redox status and conformation of the regulatory N-terminal domain of ATP7B. LeShane ES, Shinde U, Walker JM, Barry AN, Blackburn NJ, Ralle M, Lutsenko S. J Biol Chem. 2010 Feb 26;285(9):6327-36. http://www.ncbi.nlm.nih.gov/pubmed/20032459
Long-term outcome following ilioinguinal neurectomy for chronic pain. Zacest AC, Magill ST, Anderson VC, Burchiel KJ. J Neurosurg. 2010 Apr;112(4):784-9.http://www.ncbi.nlm.nih.gov/pubmed/19780646
microRNA-132 regulates dendritic growth and arborization of newborn neurons in the adult hippocampus. Magill ST, Cambronne XA, Luikart BW, Lioy DT, Leighton BH, Westbrook GL, Mandel G, Goodman RH. Proc Natl Acad Sci U S A. 2010 Nov 23;107(47):20382-7. Epub 2010 Nov 8. http://www.ncbi.nlm.nih.gov/pubmed/21059906
Molecular imaging of activated von Willebrand factor to detect high-risk atherosclerotic phenotype. McCarty OJ, Conley RB, Shentu W, Tormoen GW, Zha D, Xie A, Qi Y, Zhao Y, Carr C, Belcik T, Keene DR, de Groot PG, Lindner JR. JACC Cardiovasc Imaging. 2010 Sep;3(9):947-55 http://www.ncbi.nlm.nih.gov/pubmed/20846630
Preoperative magnetic resonance imaging in Type 2 trigeminal neuralgia. Zacest AC, Magill ST, Miller J, Burchiel KJ. J Neurosurg. 2010 Sep;113(3):511-5. http://www.ncbi.nlm.nih.gov/pubmed/20113162
Role of HSP90 in Biogenesis of the B-cell ATP-Sensitive Potassium Channel Complex. Yan FF, Pratt EB, Chen PC, Wang F, Skach WR, David LD, and Shyng SL. Mol Biol Cell. 2010 Jun 15;21(12):1945-54. Epub 2010 Apr 28. http://www.ncbi.nlm.nih.gov/pubmed/20427569
Small Molecule Inhibition of HIV-1-Induced MHC-I Downregulation Identifies a Temporally Regulated Switch in Nef Action. Dikeakos JD, Atkins KM, Thomas L, Emert-Sedlak L, Byeon IJ, Jung J, Ahn J, Wortman MD, Kukull B, Saito M, Koizumi H, Williamson DM, Hiyoshi M, Barklis E, Takiguchi M, Suzu S, Gronenborn AM, Smithgall TE, Thomas G. Mol Biol Cell. 2010 Oct 1;21(19):3279-92. http://www.ncbi.nlm.nih.gov/pubmed/20702582
The role of calcium-independent phospholipase A2 in cardiolipin remodeling in the spontaneously hypertensive heart failure rat heart. Zachman DK, Chicco AJ, McCune SA, Murphy RC, Moore RL, Sparagna GC. J Lipid Res. 2010 Mar;51(3):525-34. Epub 2009 Sep 9. http://www.ncbi.nlm.nih.gov/pubmed/19741254
Tolerance to the antinociceptive effect of morphine in the absence of short-term presynaptic desensitization in rat periaqueductal gray neurons. Fyfe LW, Cleary DR, Macey TA, Morgan MM, Ingram SL. J Pharmacol Exp Ther. 2010 Dec;335(3):674-80. Epub 2010 Aug 25 http://www.ncbi.nlm.nih.gov/pubmed/20739455
2009
Molecular biology, genetics and biochemistry of the repulsive guidance molecule family. Severyn CJ, Shinde U, Rotwein P. Biochem. J. (2009) v422:393-403 http://www.ncbi.nlm.nih.gov/pubmed/19698085
Sulfonylurea receptor 1 mutations that cause opposite insulin secretion defects with chemical chaperone exposure. Pratt EB, Yan FF, Gay JW, Stanley CA, Shyng SL. Journal of Biological Chemistry. 2009 Mar 20;284(12):7951-9. http://www.jbc.org/content/284/12/7951.long
