List of publications
About
MD/PhD students are involved in a wide variety of research projects across the OHSU campuses. Below are some of their recent journal articles.
Publications
2012
A HIF-Regulated VHL-PTP1B-Src Signaling Axis Identifies a Therapeutic Target in Renal Cell Carcinoma. Suwaki N, Vanhecke E, Atkins KM, Graf M, Swabey K, Huang P, Schraml P, Moch H, Cassidy AM, Brewer D, Al-Lazikani B, Workman P, De-Bono J, Kaye SB, Larkin J, Gore ME, Sawyers CL, Nelson P, Beer TM, Geng H, Gao L, Qian DZ, Alumkal JJ, Thomas G, Thomas GV. (2011).Sci Transl Med, 3(85):85ra47. PMID: 21632985
Differential susceptibility to axonopathy in necrotic and non-necrotic perinatal white matter lesions. Riddle A, Maire J, Gong X, Kroenke CD, Hohimer AR and SA Back. Stroke. 2012 Jan;43(1):178-84. Epub 2011 Nov 10.
Electrophysiological Measures of Auditory Processing in Patients with Multiple Sclerosis. Folmer RL, Hutter MM, Lilly DJ, Shannon J, Casiana L, Wilmington D, Lewis MS, Billings CJ, Krisky C, Berlow YA, Pollaro J, Rooney WD, and Bourdette D.Seminars in Hearing. 2012; 33(3):274-282 (In Press.)
Engineered interaction between SUR1 and Kir6.2 that enhances ATP sensitivity in KATP channels.Pratt EB, Zhou Q, Gay JW, Shyng SL. August 6 2012, Journal of General Physiology.
Friend of GATA (FOG) interacts with the Nucleosome Remodeling and Deacetylase Complex (NuRD) to support primitive erythropoiesis in Xenopus laevis. Mimoto MS, and Christian JL PLoS One. 2012 Jan;7(1):e29882.
Impaired placental nutrient transport in mice generated by in vitro fertilization. Bloise E, Lin W, Liu X, Simbulan RK, Kolahi KS, Petraglia F, Maltepe E, Donjacour A, Rinaudo PF. Endocrinology. May 4, 2012
MRI Correlates of Dichotic Listening Performance in Multiple Sclerosis.Berlow YA, Pollaro J, Krisky C, Snodgrass M, Kohout K, Lewis MS, Wilmington D, Hutter M, Casiana L, Fitzpatrick M, Lilly DJ, Fausti S, Folmer R, Bourdette D, and Rooney WD. Seminars in Hearing. 2012; 33(3):283-294
Myelination failure in human perinatal white matter injury: A disrupted cellular repair mechanism linked to pre-oligodendrocyte maturation arrest. Buser, JR, Maire, J, Riddle, A, Nelson, K, Gong, X, Luo, NL, Ren, J, Nguyen, T, Struve, J, Sherman, LS, Miller, SP, Chau, V, Hendson, G, Ballabh, P Grafe, MR and SA Back, Ann Neurol. 2012 Jan;71(1):93-109
2011
Adenosine kinase determines the degree of brain injury after ischemic stroke in mice. Shen HY, Lusardi TA, Williams-Karnesky RL, Lan JQ, Poulsen DJ, Boison D. J Cereb Blood Flow Metab. 2011 Mar 23. http://www.ncbi.nlm.nih.gov/pubmed/21427729
An organotypic slice culture model of chronic white matter injury with maturation arrest of oligodendrocyte progenitors. Dean JM, Riddle A, Maire J, Hansen KD, Preston M, Barnes AP, Sherman LS, Back SA. Mol Neurodegener. 2011 Jul 5;6:46.
ATP activates ATP-sensitive potassium channels composed of mutant sulfonylurea receptor 1 and Kir6.2 with diminished PIP2 sensitivity. Pratt EB and Shyng SL. Channels (Austin). 2011 Jul-Aug; 5(4):314-9. Epub 2011 Jul 1. (Invited article)
Central nervous system inflammation induces muscle atrophy via activation of the hypothalamic-pituitary-adrenal axis.Braun TP, Zhu X, Szumowski M, Scott GD, Grossberg AJ, Levasseur PR, Graham K, Khan S, Damaraju S, Colmers WJ, Baracos VE, Marks DL.(2011).J Exp Med.
Endothelium-derived hyperpolarizing factor in the brain: influence of sex, vessel size and disease state. Davis CM, Siler DA, Alkayed NJ. Womens Health (Lond Engl). 2011 May;7(3):293-303.
Histopathological correlates of magnetic resonance imaging-defined chronic perinatal white matter injury. Riddle A, Dean J, Buser JR, Gong X, Maire J, Chen K, Ahmad T, Cai V, Nguyen T, Kroenke CD, Hohimer AR, Back SA. Ann Neurol. 2011 Sep;70(3):493-507. doi: 10.1002/ana.22501. Epub 2011 Jul 27.
Inflammation-induced lethargy is mediated by suppression of orexin neuron activity. Grossberg A.J., Zhu X.X., Leinninger G.M., Levasseur P.L., Braun T.P., Myers, Jr. M.G., Marks D.L..J Neurosci 31(31): 11376-86 (2011). PMID21813697
Laboratory-Developed Test-SynFRAME: An Approach for Assessing Laboratory-Developed Tests Synthesized from Prior Appraisal Frameworks.Hornberger J, Doberne J, Chien R. Genet Test Mol Biomarkers. 2012 Jun ;16(6):605-14. Epub 2012 Feb 2
Maternal High Fat Diet Is Associated with Decreased Plasma n-3 Fatty Acids and Fetal Hepatic Apoptosis in Nonhuman Primates. Grant WF, Gillingham MB, Batra AK, Fewkes NM, Comstock SM, Takahashi D, Braun TP, Grove KL, Friedman JE, Marks. PLoS One. Feb. 2011.
miR-132 mediates the integration of newborn neurons into the adult dentate gyrus. Luikart BW, Bensen AL, Washburn EK, Perederiy JV, Su KG, Li Y, Kernie SG, Parada LF, Westbrook GL. PLoS One. 2011;6(5):e19077. Epub 2011 May 17.
N-terminal transmembrane domain of SUR1 controls gating of Kir6.2 by modulating channel sensitivity to PIP2. Pratt EB, Tewson P, Bruederle CE, Skach WR, Shyng SL.Journal of General Physiology. 2011 Feb 14. http://jgp.rupress.org/content/early/2011/02/09/jgp.201010557.long
Pain experienced using two different methods of endometrial biopsy: a randomized controlled trial. Leclair CM, Zia JK, Doom CM, Morgan TK, Edelman AB. Obstet Gynecol. 2011 Mar;117(3):636-41. http://www.ncbi.nlm.nih.gov/pubmed/21343767
Promotion of experimental thrombus formation by the procoagulant activity of breast cancer cells.Berny-Lang MA, Aslan JE, Tormoen GW, Patel IA, Bock PE, Gruber A, McCarty OJT, Physical Biology. 2011; 8(1) 015014
Proof of Concept: Pharmacological Preconditioning with a Toll-like receptor agonists protects against cerebrovascular injury in a primate model of stroke." Bahjat R*, Williams-Karnesky R*, West G, Doyle K, Spector M, Hobbs T, Stenzel-Poore M. JCBFM.*co-first authors. J Cereb Blood Flow Metab. 2011 Feb 2
Quantitative analysis of transient and sustained transforming growth factor-b signaling dynamics. Zhike Z,*, Feng Z, Chapnick DA, Dahl M, Deng D, Klipp E, Moustakas A, and Liu X,* Molecular Systems Biology 7:492. 2011. http://www.nature.com/msb/journal/v7/n1/pdf/msb201122.pdf
Role of carrier number on the procoagulant activity of tissue factor in blood and plasma. Tormoen GW, Rugonyi S, Gruber A, McCarty OJT,Physical Biology, 2011; 8 (2011) 066005.
Role of TNF-a in virus-induced airway hyperresponsiveness and neuronal M2 muscarinic receptor dysfunction. Nie Z, Scott GD, Weis PD, Itakura A, Fryer AD, Jacoby DB. Br J Pharmacol. 2011 Sep;164(2b):444-52
S6K1 and mTOR regulate Rac1-driven platelet activation and aggregation. Aslan JE, Tormoen GW, Loren CP, Pang J, McCarty OJT, Blood, 2011; 118(11): 3129-36.
The cell giveth and the cell taketh away: An overview of Notch pathway activation by endocytic trafficking of ligands and receptors. Pratt EB*, Wentzell JS*, Maxson JE, Courter L, Hazelett D, Christian JL.Acta Histochemica. 2011 May;113(3):248-55. Epub 2010 Feb 1. http://www.ncbi.nlm.nih.gov/pubmed/20122714
The cytoplasmic domain of rhesus cytomegalovirus Rh178 interrupts translation of major histocompatibility class I leader peptide-containing proteins prior to translocation.Richards R, Scholz I, Powers C, Skach WR, Früh K. J Virol. 2011 Sep;85(17):8766-76. Epub 2011 Jun 29.
2010
Activation of OX40 augments Th17 cytokine expression and antigen-specific uveitis. Zhang Z, Zhong W, Hinrichs D, Wu X, Weinberg A, Hall M, Spencer D, Wegmann K, Rosenbaum JT. Am J Pathol. 2010 Dec;177(6):2912-20.
Age-related changes in brain energetics and phospholipid metabolism Forester BP, Berlow YA, Harper DG, Jensen JE, Lange N, Froimowitz MP, Ravichandran C, Iosifescu DV, Lukas SE, Renshaw PF, Cohen BM. NMR Biomed. 2010 Apr;23(3):242-50.
Arcuate Nucleus Proopiomelanocortin Neurons Mediate the Acute Anorectic Actions of Leukemia Inhibitory Factor via gp130.Grossberg, AJ, Scarlett, JM, Zhu, XX Bowe, DD, Batra, AK, Braun, TP, Marks, DM. Endocrinology 151(3), March 2010.
Neuropsychiatric correlates of white matter hyperintensities in Alzheimer's disease. Berlow YA, Wells WM, Ellison JM, Sung YH, Renshaw PF, Harper DG. Int J Geriatr Psychiatry.(2010). Aug;25(8):780-788. PMID: 19946864
Cross-presentation of a spread-defective MCMV is sufficient to prime the majority of virus-specific CD8+ T cells. Snyder CM, Allan JE, Bonnett EL, Doom CM, Hill AB. PLoS One. 2010 Mar 12;5(3):e9681
Deep brain stimulation does not silence neurons in subthalamic nucleus in Parkinson's patients. Carlson JD, Cleary DR, Cetas JS, Heinricher MM, Burchiel KJ. J Neurophysiol. 2010 Feb;103(2):962-7. http://www.ncbi.nlm.nih.gov/pubmed/19955287
Evasion of CD8+ T cells is critical for superinfection by cytomegalovirus. Hansen SG, Powers CJ, Richards R, Ventura AB, Ford JC, Siess D, Axthelm MK, Nelson JA, Jarvis MA, Picker LJ, Früh K. Science. 2010 Apr 2;328(5974):102-6. http://www.ncbi.nlm.nih.gov/pubmed/20360110
Genetic and pharmacologic blockade of central melanocortin signaling attenuates development of cardiac cachexia in rodent models of heart failure. Scarlett JM, Bowe DD, Zhu XX, Batra AK, Grant WF and Marks DL.J Endocrinol. 2010 Jul;206(1):121-30. Epub 2010 Apr 6.
Granulocyte-colony stimulating factor reactivates human cytomegalovirus in a latently infected humanized mouse model. Smith MS, Goldman DC, Bailey AS, Pfaffle DL, Kreklywich CN, Spencer DB, Othieno FA, Streblow DN, Garcia JV, Fleming WH, Nelson JA. Cell Host Microbe. 2010 Sep 16;8(3):284-91.
HGF upregulation contributes to angiogenesis in mice with keratinocyte-specific Smad2 deletion. Hoot KE, Oka M, Han G, Bottinger E, Zhang Q, Wang XJ. J Clin Invest. 2010 Oct 1;120(10):3606-16. doi: 10.1172/JCI43304. http://www.ncbi.nlm.nih.gov/pubmed/20852387
Economic implications of 21-gene breast cancer risk assay from the perspective of an Israeli managed healthcare organization. Klang SH, Hammerman A, Liebermann N, Efrat N, Doberne J, Hornberger JC. Value Health 2010 Jun-Jul;13(4):381-7. Epub Apr 15, 2010.
Mechanotransduction: A major regulator of homeostasis and development. Kolahi KS, Mofrad MRK. Wiley Interdisciplinary Reviews: Systems Biology and Medicine 2(6):625-39 (2010).
Long-term outcome following ilioinguinal neurectomy for chronic pain. Zacest AC, Magill ST, Anderson VC, Burchiel KJ. J Neurosurg. 2010 Apr;112(4):784-9.http://www.ncbi.nlm.nih.gov/pubmed/19780646
microRNA-132 regulates dendritic growth and arborization of newborn neurons in the adult hippocampus. Magill ST, Cambronne XA, Luikart BW, Lioy DT, Leighton BH, Westbrook GL, Mandel G, Goodman RH. Proc Natl Acad Sci U S A. 2010 Nov 23;107(47):20382-7. http://www.ncbi.nlm.nih.gov/pubmed/21059906
Molecular imaging of activated von Willebrand factor to detect high-risk atherosclerotic phenotype. McCarty OJ, Conley RB, Shentu W, Tormoen GW, Zha D, Xie A, Qi Y, Zhao Y, Carr C, Belcik T, Keene DR, de Groot PG, Lindner JR. JACC Cardiovasc Imaging. 2010 Sep;3(9):947-55
Pharmacologic Modulation of Niche Accessibility via Tyrosine Kinase Inhibition Enhances Marrow and Thymic Engraftment After Hematopoietic Stem Cell Transplantation. Fewkes N, Krauss A, Guimond M, Meadors J, Dobre S, Mackall CL. Blood, 2010.
Novel Gamma-C Cytokines As Candidates Immune Modulators In Immune Therapies for Cancer. Fewkes N, Mackall C. The Cancer Journal, July 2010.
Preoperative magnetic resonance imaging in Type 2 trigeminal neuralgia. Zacest AC, Magill ST, Miller J, Burchiel KJ. J Neurosurg. 2010 Sep;113(3):511-5. http://www.ncbi.nlm.nih.gov/pubmed/20113162
Proximal Promoter Elements Control Repulsive Guidance Molecule c/Hemojuvelin Gene Transcription in Skeletal Muscle; Severyn CJ and Rotwein P; Genomics (2010) v96:342–351 http://www.ncbi.nlm.nih.gov/pubmed/20858542
Role of HSP90 in Biogenesis of the ß-cell ATP-Sensitive Potassium Channel Complex. Molecular Biology of the Cell.Yan FF, Pratt EB, Chen PC, Wang F, Skach WR, David LD, and Shyng SL.Mol Biol Cell. 2010 Jun 15;21(12):1945-54. Epub 2010 Apr 28. http://www.ncbi.nlm.nih.gov/pubmed/20427569
Small Molecule Inhibition of HIV-1-Induced MHC-I Downregulation Identifies a Temporally Regulated Switch in Nef Action. Dikeakos JD*, Atkins KM*, Thomas L, Emert-Sedlak L, Byeon IJ, Jung J, Ahn J, Wortman MD, Kukull B, Saito M, Koizumi H, Williamson DM, Hiyoshi M, Barklis E, Takiguchi M, Suzu S, Gronenborn AM, Smithgall TE, Thomas G. Mol Biol Cell. 2010 Oct 1;21(19):3279-92.*These authors contributed equally to this work
The role of calcium-independent phospholipase A2 in cardiolipin remodeling in the spontaneously hypertensive heart failure rat heart. Zachman DK, Chicco AJ, McCune SA, Murphy RC, Moore RL, Sparagna GC. J Lipid Res. 2010 Mar;51(3):525-34. Epub 2009 Sep 9.
Timing of appearance of late oligodendrocyte progenitors coincides with enhanced susceptibility of preterm rabbit cerebral white matter to hypoxia-ischemia. Buser JR, Segovia KN, Dean JM, Nelson K, Beardsley D, Gong X, Luo NL, Ren J, Wan Y, Riddle A, McClure MM, Ji X, Derrick M, Hohimer AR, Back SA, Tan S. J Cereb Blood Flow Metab. 2010 May;30(5):1053-65. Epub 2010 Jan 13.
Tolerance to the antinociceptive effect of morphine in the absence of short-term presynaptic desensitization in rat periaqueductal gray neurons. Fyfe LW, Cleary DR, Macey TA, Morgan MM, Ingram SL. J Pharmacol Exp Ther. 2010 Dec;335(3):674-80. Epub 2010 Aug 25 http://www.ncbi.nlm.nih.gov/pubmed/20739455
