Graduate Studies Faculty

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Brian J. O'Roak, Ph.D.

Assistant Professor
Admin Unit: SOM-Molecular & Medical Genetics Department
Phone: 503-494-2740
Programs:
Molecular & Medical Genetics
Neuroscience Graduate Program
Program in Molecular & Cellular Biosciences
Public Health and Preventative Medicine
Research Interests:
autism, neurodevelopmental disorders, genetics, genomics, bioinformatics, computational, computer science, neuroscience, molecular biology, personalized medicine, Neurobiology of Disease » PubMed Listing
Preceptor Rotations
Dr. O'Roak has not indicated availability for preceptor rotations at this time.
Faculty Mentorship
Dr. O'Roak has not indicated availability as a mentor at this time.
Profile

Brian J. O’Roak, PhD, Assistant Professor in the Department of Molecular and Medical Genetics, joined the faculty on September 16th. He is affliated with PMCB and NGP.

Dr. O’Roak earned his PhD from Yale University’s Department of Genetics in 2009, working with Dr. Matthew W. State. He then went on for postdoctoral training in the Department of Genome Sciences at the University of Washington, under Drs. Evan E. Eichler and Jay Shendure.

Highlights of Dr. O’Roak’s past research successes include: developing a chromosomal outlier approach to identify candidate genes for Tourette’s syndrome and autism, pioneering family based “exome” sequencing in autism, and developing new technologies for rapid and economical targeted resequencing. He plans on building on this experience by forming a strong and diverse neurogenomics research group focused on developing and implementing cutting-edge methods and technologies for discovery and replication, molecular diagnosis, functional dissection of pathways, and targeted therapeutics for neurodevelopmental and related disorders. This work has the potential to dramatically improve the lives of individuals affected with these currently untreatable disorders through early intervention and biologically based personal therapies.