Graduate Studies Faculty
Zheng David. Qian, Ph.D.
Programs:Program in Molecular & Cellular Biosciences
Research Interests:tumor hypoxia signaling, targeted therapy, bedside to benchside reverse translation, adaptive response, immune response, treatment resistance, epigenetics, molecular biology, mouse tumor models » PubMed Listing
Preceptor RotationsAcademic Term Available Summer 2016 Yes Fall 2016 Yes Winter 2016 Yes Summer 2017 Yes Fall 2017 Yes Winter 2017 Yes Spring 2017 Yes
Faculty MentorshipDr. Qian is available as a mentor for 2016-2017. Dr. Qian is available as a mentor for 2017-2018.
Dr. Qian is a molecular and cellular cancer biologist, principal investigator, and graduate faculty at OHSU Knight Cancer Institute and School of Medicine. He received Ph.D. and postdoctoral training from Johns Hopkins University and Johns Hopkins University Kimmel Cancer Center.
Dr. Qian’s lab aims to discover novel mechanisms of cancer biology and develop precise and personalized approaches to prevent, detect, and treat human cancers. The current research projects are 1) to understand the roles of tumor hypoxia and hypoxia-inducible factor (HIF) in mediating tumor and tumor microenvironment interaction, metastatic progression, and treatment resistance; 2) to dissect the adaptive resistance pathways in response to therapeutic inhibition of HIF and tumor hypoxia signaling; 3) to determine the crosstalk between hypoxia signaling and hormonal signaling, and the impact on epigenetics, cancer cells and cancer progenitor cells, and treatment resistance.
Dr. Qian has been a NIH-funded investigator since 2010. The research approaches in his lab are multidisciplinary, including molecular and cellular biology, epigenetics, genomics, proteomics, bioinformatics, experimental therapeutics, and clinical trials.