Graduate Studies Faculty

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Rosalie Sears, PhD

Associate Professor
Admin Unit: SOM-Molecular & Medical Genetics Department
Molecular & Medical Genetics
Program in Molecular & Cellular Biosciences
Cancer Biology
Research Interests:
Cancer genetics; Proteolysis and cell cycle control; Apoptosis; Mouse models of cancer; Genomics; Signal transduction
Preceptor Rotations
Dr. Sears has not indicated availability for preceptor rotations at this time.
Faculty Mentorship
Dr. Sears has not indicated availability as a mentor at this time.

Recent Publications

Escamilla-Powers, J.R. and R.C. Sears.  2007. A conserved pathway that controls c-Myc protein stability through opposing phosphorylation events occurs in yeast. J Biol Chem. 282(8): 5432-42.

Ma, J., H.K. Arnold, M.B. Lilly, R.C. Sears and A.S. Kraft. 2007. Negative regulation of Pim-1 protein kinase levels by the B56beta subunit of PP2A. Oncogene Feb 12; [Epub ahead of print].


Junttila, M.R., P. Puustinen, M. Niemelä, R. Ahola, H. Arnold, T. Böttzauw, R. Ala-aho, C. Nielsen, J. Ivaska, Y. Taya, S-L. Lu, S. Li, E.K.L. Chan, X-J Wang, R. Grènman, J. Kast, T. Kallunki, R. Sears, V-M. Kähäri and J. Westermarck. 2007. CIP2A inhibits PP2A in human malignancies. Cell, In Press.

Dai, M-S., H. Arnold, X-X. Sun, R. Sears and H. Lu. 2007. Inhibition of c-Myc activity by ribosomal protein L11. Embo J., In Press.


O'Neil, J., J. Grim, P. Strack, S. Rao, D. Tibbitts, C. Winter, J. Hardwick, M. Welcker, J.P. Meijerink, R. Pieters, G. Draetta, R. Sears, B.E. Clurman and A.T. Look. 2007. FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to ?-secretase inhibitors. J Exp. Med., In Press.