Jean-Philippe (JP) Gourdine

JP

Senior Research Associate

gourdine@ohsu.edu

Major Responsibilities

Supporting integration and comparison of metabolomics/glycomics phenotypes and their correlation with genotypes across species for the Undiagnosed Disease Network (UDN) project

Developing ontologies with ontologists, bioinformaticians, and software engineers at OHSU and consortium sites to design and implement tools and strategies for semantically navigating and manipulating data.

Education

  • Ph.D. in Marine Biochemistry, Université des Antilles et de la Guyane, France 2002-2006
  • M.S. in Life and Earth Sciences, Université des Antilles et de la Guyane, France 1997-2002

Research and Work Experience

  • Ontologist and Data Curator, Oregon Health and Science University, Portland OR (2015-present), Advisor: Dr. Melissa Haendel
  • Patent and Technical Scientific Writer, Kolisch-Hartwell, Portland OR, (2015) Advisor: Dr Shawn Kolitch
  • Post-Doctoral Fellow in Glycobiology, Emory University, Atlanta GA, (2009-2014), Advisor: Dr. Richard D. Cummings
  • Post-Doctoral Teaching Fellow in Biochemistry in the French National Center for Scientific Research, Grenoble and Université des Antilles et de la Guyane – France (2006-2009), Advisor: Dr Juliette Smith-Ravin and Dr. Anne Imberty
  • Graduate Student, in Biochemistry, Université des Antilles et de la Guyane – France, (2006-2009), Advisor: Dr Juliette Smith-Ravin
  • Undergraduate Research Assistant, Université des Antilles et de la Guyane – France, (2006-2009), Advisor: Dr Juliette Smith-Ravin
  • Summer Research Intern, Caribbean Sickle Cell Center, Centre Hospitalier Universitaire, Pointe-a-Pitre, Guadeloupe (2000), Advisor: Dr Monique Decastel

Teaching Experience

  • Post-Doctoral Teaching Fellow in Biochemistry, Evolutionary Biology, Genetics, Université des Antilles et de la Guyane – France (2006-2009)

Editor Ad Hoc (Reviewer)

  • Cahiers Caribéens d’Egyptologie (2009-present)
  • The Protein Journal (2011)
  • Biochemical and Biophysical Acta 2010
  • Glycobiology (2009)

Grants, Awards and Honors

  • Travel Award from the American Society for Biochemistry and Molecular Biology (2012)
  • Travel Award from the Glycobiology Society (2010)
  • Grants from the French National Center for Scientific Research and Ministry of Research (2006-2009)
  • Award for most prolific PhD student in Science, Université des Antilles et de la Guyane – France (2006)
  • Regional Council of Guadeloupe Research Grant (French West Indies) (2002-2006)

Select Publications and Presentations

Publications

  • Noll A.J, Gourdine JP, Yu Y, Lasanajak Y, Smith D.F, Cummings R.D. Galectins are Human Milk Glycan receptors. Glycobiology, accepted January 2016
  • Hudson AE, Gollnick C, Gourdine JP, Prinz AA. Degradation of extracellular chondroitin sulfate delays recovery of network activity after perturbation. J. Neurophysiol. 2015 Aug;114(2):1346-52
  • Stowell SR, Arthur CM, McBride R, Berger O, Razi N, Heimburg-Molinaro J, Rodrigues LC, Gourdine JP, Noll AJ, von Gunten S, Smith DF, Knirel YA, Paulson JC, Cummings RD. Microbial glycan microarrays define key features of host-microbial interactions. Nat. Chem. Biol. 2014 Jun;10(6):470-6.
  • Stowell SR, Arthur CM, Dias-Baruffi M, Rodrigues LC, Gourdine JP, Heimburg-Molinaro J, Ju T, Molinaro RJ, Rivera-Marrero C, Xia B, Smith DF, Cummings RD. Innate immune lectins kill bacteria expressing blood group antigen. Nat. Med. 2010;16(3):295-301.
  • Gourdine J-P, Cioci G., Miguet L, Unverzagt C., Varón Silva D., Varrot A., Gautier C., Smith-Ravin E.J., and Imberty A. Crystal structure of Codakia orbicularis lectin : High affinity interaction between bivalve C-type lectin and biantennary complex-type N-glycan revealed by crystallography and microcalorimetry. J Biol Chem. 2008 ;283(44):30112-20.
  • Gourdine J.-P., Markiv A., Smith-Ravin E.J. The three-dimensional structures of codakine and related marine C-type lectins. Fish Shellfish Immunol. 2007, 23, 831-839.
  • Gourdine J.-P., Smith-Ravin E.J. Analysis of a cDNA-derived sequence of a novel mannose-binding lectin, codakine, from the tropical clam Codakia orbicularis. Fish Shellfish Immunol. 2007, 22, 498-509.
  • Gourdine J-P., Greenwell P., Smith-Ravin E.J. Application of the recombinant phage display antibody technique to the study of Codakia orbicularis gill proteins. Appl. Biochem. Biotechnol. 2005, 125, 41-52.
  • Gourdine J-P. Smith-Ravin E.J. and Greenwell P. Phage display antibody against gill protein of the tropical clam. Mol. Cell Prot. 2003, 2,(9) p 759
  • Gourdine J-P., Smith-Ravin E. J.  Electrophoretic separation of gill proteins of the clam Codakia orbicularis.  Prep. Biochem. Biotech. 2002, 32, 341-353.

Oral Presentations

  • Gourdine J-P, Arthur C.M., Stowell S.R. and Cummings RD. Galectin-8 induces PS exposure on HL60 cells through CD45 interaction. Glycobiology Conference, Saint-Petersburg, November 10th 2010
  • Gourdine J-P, Cioci G., Miguet L, Unverzagt C., Varón Silva D., Varrot A., Gautier C., Smith-Ravin E.J., and Imberty A. Characterization of codakine, a C-type lectin from gills of the bacteria-symbiotic clam Codakia orbicularis. Interlec 23rd, Edinburgh University of Edinburgh, Scotland, July 11th – 16th 2008
  • Gourdine J-P., Smith-Ravin E.J. Marine biotechnology prospectives in the Caribbeans, a study of gill proteins of the tropical bivalve Codakia orbicularis, Caribbean Academy of Science Meeting, Gosier, Guadeloupe, French West Indies, May 2006.
  • Gourdine J-P., Smith-Ravin E.J. Novel cDNA derived-sequence of a major Codakia orbicularis gill proteins, International Congress of Marine Biotechnology, St-John’s, Newfoundland, Canada, June 2005.