Klaus Früh, Ph.D.

Figure 3: Cluster analysis of genes changing in response to IFN, gB or HCMV infection. Genes changing more than 2.3-fold in each of the treatments were selected for hierachical cluster analysis (using log e transforms of the ratios) with the OmniViz Protm software package using the CorScapetm visualization. Depicted ratios were derived by comparing hybridization signals obtained from virus, gB or interferon treated cells to those of mock treatments. Each gene is represented as a horizontal strip, with the color representing the relative linear induction or repression ratio as depicted by the color scale. The distribution of the genes into distinct clusters (shown in the gray sidebar) was generated with OmniViz Protm software, and the clusters are similarly ordered according to the hierarchical correlation algorithm used. (From: Simmen et al., Proc. Natl. Acad. USA, 2001, 98:7140-7145).

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