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Monoclonal antibodies against the rat GluA2 AMPA receptor (14B11 and 15F1)

 

OHSU # 1671

Technology Overview:

The 14B11 and 15F1 antibodies are mouse-derived monoclonal antibodies that bind with high affinity and specificity to the rat GluA2 AMPA receptor.  They are exceptional reagents for labeling the intact receptor under native (biological) conditions and can be used for a wide variety of imaging applications. They are not useful, however, for Western blotting, because they recognize 3 dimensional epitopes on the folded, intact receptor. 

 

Additional information can be found in the following articles:

Giannone G, et al.  Biophys J. 2010 Aug 9;99(4):1303-10

Nair et al. J. Neurosci. 2013 33, 13204-24

Constals et al. Neuron 2015 85, 787-803

 

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Trina Voss
Technology Development Manager
503-494-9839