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Super-Resolution Image Analysis for 2D/3D Reconstruction

 

OHSU # 2142

Technology Overview:

A professor at Oregon Health & Science University has developed a novel algorithm that can be incorporated into digital imaging systems to create super-resolution (SR) images beyond the camera Nyquist frequency. The broad utility of the algorithm enables sharper, more detailed images to be reconstructed from sensitive imaging instruments such as:

 

• Electron microscopes             • Medical CT imaging

  • Light microscopes                   • Photograph cameras

  • Telescopes                                • Surveillance imaging

 

Single-Particle EM Reconstruction (A) A reconstructed SR density map (gold) of the 20S protesome, in which the resolution has reached 5.3 Å (the Nyquist frequency of raw images is 8.0 Å). (B) For comparison, the 3D reconstruction by the conventional method (gray) using the same data is at much lower resolution.

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PublishedUnited StatesUS 2017/0053378

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Trina Voss
Technology Development Manager
503-494-9839