Categories | Inventors
A Novel Human Dopamine Receptor and its Uses (D4 subtypes - D4.2,4.4,4.7)
OHSU # 0250
Categories:
- Biological Materials - Receptors/Targets
- Research Tools - Screening
- Biological Materials
- Research Tools
Inventors:
- Olivier Civelli
- Hubert Henri-Marie Van Tol
- James Bunzow, VI.Vollum Institute
- David Grandy, SM.Physiology & Pharmacology
Technology
Overview
Technology
0250 is directed toward the isolation, characterization and pharmacological use
of the human D4 dopamine receptor. The nucleotide sequence of the gene
corresponding to this receptor and allelic variant thereof are provided by the
invention.
The invention also includes recombinant eukaryotic expression constructs capable of expressing the human D4 dopamine receptor in cultures of transformed eukaryotic cells. The invention provides cultures of transformed eukaryotic cells which synthesize the human D4 dopamine receptor, and methods for characterizing novel psychotropic compounds using such cultures.
Patents:
| Issued | United States | 5,883,226 |
For more information, contact:
Travis Cook
Technology Development Manager
503-494-3229
