Durable Dental Composites
OHSU # 1962
A light-cured, dental resin composite for all types of restorations combining thiourethane oligomers with methacrylamide monomers to increase strength, biocompatibility and durability.
An innovative resin composite to improve the lifetime of dental restorations without modifying clinical protocols of applying dental restoration materials. The addition of novel oligomers to existing commercial products would not change application protocols leading to acceptance by dental practices.
Problem: Current dental resin composites last, on average, between 5-10 years due to fracture and degradation. Polymerization shrinkage and stress cause degradation at the tooth interface leading to restoration failure. To date, materials developed to reduce polymerization shrinkage and stress have proven inefficient at extending the life span of restorations.
Solution: Carmem Pfeifer, D.D.S., Ph.D., developed resin composites that reduce polymerization shrinkage by 10-20% and reduce polymerization stress by 50-75% as compared to current resin composites. In addition, the mechanical properties of the resin are significantly improved, allowing for more reliable dental composites.
Dental caries are a prevalent public health issue, especially evident in under served populations in the U.S. Recurring decay and fracture cause hundreds of thousands of resin composite dental restorations to be replaced each year. The average life span of resin composite restorations is 7 years; factors that influence longevity include polymerization shrinkage, polymer stress, material degradation and material fracture.
With 60-90% of school-aged children and the vast majority of adults being affected by dental caries, the dental repair and restoration industry is a fast growing market. Additionally, aging baby-boomers with increased incomes can afford better and more aesthetically pleasing dental choices. In 2011, the US dental market size was $164.5 million with a CAGR (compound annual growth rate) of 5.3% expected between 2011 and 2018. The dental repair and restorative market represents approximately 7% of the overall US dental market.
Bacchi A., Consani R.L., Martim, G.C., Pfeifer, C.S. Thio-urethane oligomers improve the properties of light-cured resin cements. Dent Mater. 2015; 31(5): 565-574;
Bacchi A., Consani R.L., Ferracane, J. L., Pfeifer, C.S. Thio-urethane oligomers improve the properties of dual-cured resin cements. J Dent Res. 2014; 93(12): 1320-1325;
Pfeifer, C.S., Wilson, N.D., Shelton, Z.R., Stansbury, J.W. Delayed gelation through chain-transfer reactions: mechanism for stress reduction in methacrylate. Polymer. 2011; 52(15): 3295-3303.
U.S. Provisional patent application filed 03/17/2014
PCT patent application filed 03/17/2015
US non-provisional patent application filed 9/16/2016
- Carmem Pfeifer, SD.Restorative Dentistry
|Notice of allowance||United States|
Other Patents Filed
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Technology Development Manager