Recent Articles of Interest
Hereditary hemochromatosis genotypes and risk of ischemic stroke
Neurology. 2007 Mar 27; 68(13) : 1025-31
Hereditary hemochromatosis H63D homozygosity predicts a two- to threefold risk of ischemic cerebrovascular disease and ischemic stroke. A mutation in the hemochromatosis gene (HFE) has been associated with a three times higher risk of stroke in a group of 9000 people in Denmark. The H63D mutation (His63Asp) changes the size or function of the HFE protein so that it can't play a part in regulating the amount of iron that enters cells. Read Abstract »