The federal Office of Management and Budget (OMB) has issued a number of Circulars to define the principles and standards for agreements between federal agencies and research institutions. The three Circulars most relevant to OHSU are A-21, A-110, and A-133. Detailed and complex, these Circulars can be difficult to understand, but a clear grasp of their central principles is essential for effective sponsored project management. This Post-award Education Program (PEP) course provides department administrative staff a strong foundation in OMB Circulars and their significance to sponsored project management at OHSU.