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191 result(s) for Hematologic Cancers

PI Name Protocol # Title
Edward Neuwelt IRB00000922 Phase II Clinical Trial of Patients with High-Grade Glioma Treated with Intra-arterial Carboplatin-based Chemotherapy, Randomized to Treatment with or without Delayed Intravenous Sodium Thiosulfate as a Potential Chemoprotectant against Severe Thrombocytopenia
Edward Neuwelt IRB00001012 A Phase II Study of Patients with Newly Diagnosed Primary Central Nervous System Lymphoma Treated with Methotrexate/BBBD, and Adding Rituximab (an anti CD-20 Antibody) and Carboplatin, to the Treatment Regimen
Bonnie Nagel IRB00002560 Neurocognition and Brain Development in Youth (Attention Deficit)
Edward Neuwelt IRB00002868 Phase I/II Study of Carboplatin, Melphalan and Etoposide Phosphate in Conjunction with Osmotic Opening of the Blood-Brain Barrier and Delayed Intravenous Sodium Thiosulfate Chemoprotection, in Previously Treated Subjects with Anaplastic Oligodendroglioma or Oligoastrocytoma
Vassiliki Tsikitis IRB00003082 Oregon Colorectal Cancer Registry
David Koeller IRB00003120 A Global, Multi-Center, Long-Term, Observational Survey of Patients with Hunter Syndrome (Mucopolysaccharidosis II) - Hunter Outcome Survey (HOS)
Brett Sheppard IRB00003609 Oregon Pancreas Tumor Registry
Shoukhrat Mitalipov IRB00003892 [STEM CELLS] Histocompatible human pluripotent cells
Fay Horak IRB00004131 Exercise, Brain Imaging, Cognition, and Gait in Parkinsonism
Edward Neuwelt IRB00005056 Phase I/II Study of Intra-arterial Melphalan Given with Intra-arterial Carboplatin, Osmotic Blood-Brain Barrier Disruption and Delayed Otoprotective Sodium Thiosulfate for Patients with Recurrent or Progressive CNS Embryonal or Germ Cell Tumors
Kevin Billingsley IRB00005222 Oregon Liver Tumor Registry
Damien Fair IRB00005239 Typical and Atypical Brain Development
Tomasz Beer IRB00005688 A Phase II study of MAOA inhibitor plus docetaxel in patients receiving and progressing on docetaxel therapy
David Lieberman IRB00006137 PVAMC / OHSU: Cruciferous Vegetable Intake and Histone Status in Screening Colonoscopy Patients
Kathleen Kemmer IRB00006256 I-SPY 2 TRIAL: Investigation of Serial Studies to Predict Your Therapeutic Response with Imaging and Molecular Analysis 2
Joel Nigg IRB00006258 Longitudinal Brain Imaging Study of ADHD
Chad Hagen IRB00006308 Unobtrusive measurement of sleep disordered breathing in the home
Penelope Hogarth IRB00006459 The Parkinson's Progression Markers Initiative (PPMI)
Shoukhrat Mitalipov IRB00006709 [STEM CELLS] Mitochondrial gene replacement in human oocytes
Joel Nigg IRB00006749 Developmental Origins of Attention Deficit Hyperactivity Disorder
Daniel Clayburgh IRB00006918 RTOG 0920: A Phase III Study of Postoperative Radiation Therapy (IMRT) +/- Cetuximab for Locally-Advanced Resected Head and Neck Cancer
Stephen Spurgeon IRB00007195 A Phase II Proof of Concept Trial to Study Kinase Inhibition in Relapsed/Refractory Acute Leukemias: Using a Comprehensive in Vitro Kinase Inhibitor Panel to Select Individualized Targeted Therapies
Christopher Ryan IRB00007404 S0931 EVEREST: EVErolimus for Renal Cancer Ensuing Surgical Therapy, A Phase III Study
Eric Simpson IRB00008446 Skin Barrier Function Assessment in Rare Diseases Caused by Abnormal Sterol and Isoprenoid Metabolism: A Pilot Study
Charles Henrikson IRB00008728 Standard v. Enhanced MRI-Guided Ablation in the Treatment of Ventricular Tachycardia
Joshi Alumkal IRB00008791 The Role of Highly Selective Androgen Receptor (AR) Targeted Therapy in Men with Biochemically Relapsed Hormone Sensitive Prostate Cancer
William Hoffman IRB00008874 PVAMC / OHSU J: Pilot study of the dose response of entacapone on methamphetamine induced interest, mood elevation, and reward
Andy Chen IRB00008906 GO27834: A Randomized, Open-Label, Multicenter, Phase II Trial Evaluating the Safety and Activity of pinatuzumab vedotin (DCDT2980S) in Combination with Rituximab or Polatuzumab Vedotin (DCDS4501A) in Combination with Rituximab and A Non Randomized phase Ib/II Evaluation of Polatuzumab Vedotin in Combination with Obinutuzumab in Patients with Relapsed or Refractory B-cell Non- Hodgkin’s Lymphoma
Sonemany Salinthone IRB00008908 PVAMC / OHSU: Elucidating the Mechanisms that Mediate the Effects of Lipoic Acid in Multiple Sclerosis
Fay Horak IRB00008979 Frontal Cortex and Gait Freezing in Parkinson's Disease: Rehabilitation Impact
Charles Thomas IRB00009013 A Study to Determine the Immune Profile of Rectal Adenocarcinoma and its Correlation with the Efficacy of Neoadjuvant Chemoradiotherapy
Kathleen Kemmer IRB00009076 A phase III randomized, double blind, placebo controlled study of BKM120 with fulvestrant, in postmenopausal women with hormone receptor-positive HER2-negative AI treated, locally advanced or metastatic breast cancer who progressed on or after mTOR inhibitor based treatment
Kristen Mackiewicz Seghete IRB00009182 Neural Mechanisms of Cognitive Inhibition in Youth with and without a Trauma History
Tomasz Beer IRB00009204 Radiologically Guided Biopsies of Metastatic Castration Resistant Prostate Cancer to Identify Adaptive Mechanisms of Resistance
Christopher Ryan IRB00009241 Randomized, Double-Blind Phase III study of Pazopanib vs Placebo in Patients with Metastatic Renal Cell Carcinoma Who Have No Evidence of Disease Following Metastatectomy
Joshi Alumkal IRB00009259 Identifying Mechanisms of Resistance to Enzalutamide (MDV3100) Treatment in Men with Castration-Resistant Prostate Cancer
Winston Chamberlain IRB00009280 Randomized Clinical Trial of OCT-Guided Laser-Assisted Lemellar Anterior Keratoplasty in Adults for Keratoconus
Winston Chamberlain IRB00009282 Randomized Clinical Trial of OCT-Guided Laser-Assisted Lamellar Anterior Keratoplasty in Adults for Stromal Opacities
Saurabh Gupta IRB00009290 Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart Failure Patients with Functional MR (The COAPT Trial)
Charlotte Kubicky IRB00009340 Impact of Breast Conservation Surgery on Surgical Outcomes and Cosmesis in Patients with Multiple Ipsilateral Breast Cancers (MIBC)
Julie Graff IRB00009352 A phase 2, randomized, 3-arm study of abiraterone acetate alone, abiraterone acetate plus degarelix, a GnRH antagonist, and degarelix alone for patients with prostate cancer with a rising PSA or a rising PSA and nodal disease following definitive radical prostatectomy
Julie Graff IRB00009363 PVAMC / OHSU J: A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Phase III Study of ARN-509 in Men with Non-Metastatic (M0) Castration-Resistant Prostate Cancer
Richard Maziarz IRB00009375 A Phase 1-2 Dose Escalation Study Evaluating Safety and Feasibility of BPX-501 T Cells after Partially Mismatched, Related, T Cell-Depleted HSCT
Emma Scott IRB00009398 A Randomized Phase III Study Comparing Conventional Dose Treatment Using a Combination of Lenalidomide, Bortezomib and Dexamethasone (RVD) to High-Dose Treatment with Peripheral Stem Cell Transplant in the Initial Management of Myeloma in Patients up to 65 Years of Age
Rodney Pommier IRB00009420 Oregon Index of Endocrine Neoplasias (ORION)
Emma Scott IRB00009421 A Phase I Dose-Escalation Study of Carfilzomib in Patients with Previously-Treated Systemic Light-Chain (AL) Amyloidosis
Kevin Winthrop IRB00009463 The Oregon nontuberculous mycobacteria (NTM) cohort; immune correlates of pulmonary NTM disease progression
Christopher Ryan IRB00009464 A Phase II Study of Sorafenib with Chemotherapy, Radiation, and Surgery for High-Risk Soft Tissue Sarcomas
Matthew Taylor IRB00009480 A Randomized, Double Blind Study to Compare the Complete Remission Rate Following a 5-Week Course of Selumetinib or Placebo and Single Dose Adjuvant Radioactive Iodine Therapy in Patients with Differentiated Thyroid Cancer
Richard Maziarz IRB00009571 A Phase II, Randomized Trial of Standard of Care with or without Midostaurin to Prevent Relapse Following Allogeneic Hematopoietic Stem Cell Transplantation in Patients with FLT3-ITD Mutated Acute Myeloid Leukemia
Richard Maziarz IRB00009585 Prospective Multi-Center Cohort for the Evaluation of Biomarkers Predicting Risk of Complications and Mortality Following Allogeneic HCT
Scott Chadderdon IRB00009594 Cardiovascular Inflammation Reduction Trial (CIRT)
Erin Gilbert IRB00009694 The Use of Dynamic Contrast Enhanced Magnetic Resonance Imaging (DCE MRI) in the Management of Pancreatic Cancer
Emma Scott IRB00009761 A Phase 3, Randomized, Double-Blind, Multicenter Study Comparing Oral MLN9708 Plus Lenalidomide and Dexamethasone Versus Placebo Plus Lenalidomide and Dexamethasone in Adults With Newly Diagnosed Multiple Myeloma
Michael Shapiro IRB00009813 International Study of Comparative Health Effectiveness with Medical and Invasive Approaches (ISCHEMIA)
Lynne Shinto IRB00009880 Omega 3 PUFA for the vascular component of age-related cognitive decline
Akram Khan IRB00009885 Safety and Efficacy of A Lysophosphatidic Acid Receptor Antagonist in Idiopathic Pulmonary Fibrosis IM136003
Matthew Taylor IRB00009902 A Phase 1/2, Open-label Study of Nivolumab Monotherapy or Nivolumab combined with Ipilimumab in Subjects with Advanced or Metastatic Solid Tumors
Fay Horak IRB00009903 Characterization and Treatment of Gait Disturbances in Parkinson's disease
Jeffrey Kaye IRB00010057 A Seamless Phase IIa/IIb, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel Group Trial to Evaluate the Efficacy and Safety of MK-7622 as an Adjunctive Therapy for Symptomatic Treatment in Subjects with Alzheimer’s Disease. MK-7622-012
Steven Shea IRB00010101 Circadian rhythms and cardiovascular risk
Paul Spellman IRB00010163 Reconstructing the Tumor Genome in Peripheral Blood
Lucinda Hugos IRB00010164 PVAMC / OHSU J: Developing and Testing a Comprehensive MS Spasticity Management Program
Matthew Taylor IRB00010177 A Phase I, Open-Label, Multiple-Ascending Dose Trial to Investigate the Safety, Tolerability, Pharmacokinetics, Biological and Clinical Activity of avelumab (MSB0010718C) in Subjects with Metastatic or Locally Advanced Solid Tumors and Expansion to Selected Indications
Kevin Winthrop IRB00010178 The Safety and Effectiveness of the VaricElla zosteR VaccinE (VERVE) in Anti-TNF Users Trial
Donna Graville IRB00010199 The effect of age and bolus consistency on the swallowing efficiency of adults with and without dysphagia
Joshi Alumkal IRB00010241 Molecular Mechanisms Underlying Tumor Progression Despite Enzalutamide Treatment
Kim-Hien Dao IRB00010262 Prospective Evaluation of ruxolitinib Efficacy for CNL/aCML Patients with Mutation of CSF3R
Lisa Silbert IRB00010264 Protocol H8A-MC-LZAZ(a)/ADC-040-A4 Anti-Amyloid Treatment in Asymptomatic Alzheimer’s Disease (A4 Study)
Xin Li IRB00010345 Contrast Enhanced MRI of the Prostate
Stephen Heitner IRB00010369 A Phase 2/3 Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of ISIS 420915 in Patients with Familial Amyloid Polyneuropathy (ISIS 420915-CS2 FAP)
Laura Carim Todd IRB00010373 Behavioral Interventions to Target Self-Control
Stephen Spurgeon IRB00010383 A Phase 1 Dose Escalation and Cohort Expansion Study of the Safety, Tolerability, and Efficacy of Anti-Lag-3 (BMS-986016) in Relapsed or Refractory Chronic Lymphocytic Leukemia and Lymphomas
Akram Khan IRB00010386 A Multicenter, Double-Blind, Randomized, Placebo-Controlled, Phase 3 Study to Assess the Efficacy and Safety of Oral BPS 314d-MR Added-On to Treprostinil, Inhaled (Tyvaso®) in Subjects with Pulmonary Arterial Hypertension
Kevin Winthrop IRB00010433 A pilot study for the Varicella Zoster Vaccine (VERVE) Trial
Tomasz Beer IRB00010479 A Randomized, Double Blind, Multicenter, Parallel-group, Phase III Study to Evaluate Efficacy and Safety of DCVAC/PCa Versus Placebo in Men with Metastatic Castration Resistant Prostate Cancer Eligible for 1st Line Chemotherapy
Saurabh Gupta IRB00010503 Portico Re-sheathable Transcatheter Aortic Valve System US IDE Trial (PORTICO)
Kerri Winters IRB00010504 Whole Body Vibration Training for Healthy Body Composition in Young Adults
Frederick Tibayan IRB00010527 A Prospective, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of Preoperative Antithrombin Supplementation in Patients Undergoing High-Risk Cardiac Surgery with Cardiopulmonary Bypass (GTI-1307)
Lara Davis IRB00010529 SARC024: A blanket protocol to study oral regorafenib in patients with refractory liposarcoma, osteogenic sarcoma, and Ewing/Ewing–like sarcomas
Steven Bailey IRB00010535 Optical coherence tomography angiography in neovascular age-related macular degeneration
Michael Heinrich IRB00010537 A Phase I, Multicenter, Open-Label Study of Oral ABL001 in Patients with Chronic Myelogenous Leukemia or Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia
Charles Henrikson IRB00010538 Late Sodium Current Blockade in High-Risk ICD Patients - Ranolazine ICD Trial (RAID)
Charles Lopez IRB00010540 A Phase III, Multicenter, Open-Label, Randomized Study of nab-Paclitaxel Plus Gemcitabine Versus Gemcitabine Alone as Adjuvant Therapy in Subjects with Surgically Resected Pancreatic Adenocarcinoma
Kimberly Mauer IRB00010548 Functional Imaging of Light-Induced Activation of Pain-Related Circuitry in Fibromyalgia as a Marker for Central Sensitization
Sancy Leachman IRB00010561 War on Melanoma: Enlisting a cohort of melanoma survivors and their families
Cailin Sibley IRB00010580 Risk for Development of ANCA in First-Degree Relatives of Patients with ANCA-Associated Vasculitis
Matthew Taylor IRB00010605 A Phase I, Open-Label, Multicentre Study to Assess the Safety, Tolerability, Pharmacokinetics and Preliminary Anti-tumour Activity of Ascending Doses of AZD5363 under Adaptable Dosing Schedules in Patients with Advanced Solid Malignancies
Peter Andersen IRB00010613 Phase II Randomized Trial of Transoral Surgical Resection followed by Low-dose or Standard-dose IMRT in Resectable p16+ Locally Advanced Oropharynx Cancer
Stephen Heitner IRB00010645 A Phase 2/3, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Effect of GS-6615 on Exercise Capacity in Subjects with Symptomatic Hypertrophic Cardiomyopathy (GS-US-361-1157)
Elie Traer IRB00010674 A Phase 3 Open-Label Randomized Study of Quizartinib (AC220) Monotherapy Versus Salvage Chemotherapy in Subjects with FLT3-ITD Positive Acute Myeloid Leukemia (AML) Refractory to or Relapsed after First-Line Treatment With or Without Hematopoietic Stem Cell Transplantation (HSCT) Consolidation
Stephen Heitner IRB00010707 Novel Predictors of Outcome in Hypertrophic Cardiomyopathy (HCMR)
Peter Jacobs IRB00010708 Improving speech intelligibility in noise through an interactive video game
Mary Samuels IRB00010709 OCTRI Research Volunteer Registry
Rahel Nardos IRB00010729 Urinary Microbiomes: Do they play a role in Urgency Urinary Incontinence?
John Nutt IRB00010745 Effects of augmenting cholinergic function on gait and balance
Andrew Riley IRB00010750 Parent and Provider Perceptions of Behavioral Video Tutorials in Pediatric Primary Care
Joseph Quinn IRB00010809 A Randomized, Double-Blind, Placebo-Controlled, Multiple Ascending Dose Study of PRX002 Administered By Intravenous Infusion in Patients with Parkinson's Disease
Barry Oken IRB00010810 Improving sleep quality in people with insomnia
Lissi Hansen IRB00010828 Mother-Daughter Care Dyad Relationships in the Context of Hospice at Home
Kim-Hien Dao IRB00010849 A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study of Azacitidine with or without Birinapant with a Single Arm Open-Label Run-In Phase in Subjects with Higher Risk Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia
Eric Anderson IRB00010866 Safety and Efficacy of nab®-paclitaxel (Abraxane®) in Combination with Carboplatin as First Line Treatment in Elderly Subjects with Advanced Non-Small Cell Lung Cancer (NSCLC): A Phase IV, Randomized, Open-Label, Multicenter Study
Michael Heinrich IRB00010886 A companion sample collection protocol to support the discovery of the mechanisms of resistance to targeted cancer therapies.
Richard Maziarz IRB00010941 A Multi-center Phase II Trial Randomizing Novel Approaches for Graft-versus-Host Disease Prevention Compared to Contemporary Controls
Thomas Hwang IRB00010949 Functional Optical Coherence Tomography-Derived Biomarkers for Diabetic Retinopathy
Julie Graff IRB00011025 PVAMC / OHSU J: Addition of Pembrolizumab Upon Progression on Enzalutamide in men with mCRPC
Jeremy Cetnar IRB00011046 S1400, Phase II/III Biomarker-Driven Master Protocol for Second Line Therapy of Squamous Cell Lung Cancer
Rachel Cook IRB00011076 A Phase I Dose Escalation with Two Disease Specific Expansions, Multicenter, Open-label, Safety, Pharmacokinetic and Pharmacodynamic Study of LOR-253 in Patients with Relapsed or Refractory Hematologic Malignancies
Emma Scott IRB00011097 A Feasibility Study of Myeloablative BEAM Allogeneic Transplantation Followed by Oral Ixazomib Maintenance Therapy in Patients with Relapsed High-Risk Multiple Myeloma
Emma Scott IRB00011120 A Phase I Open Label Dose Escalation and Randomized Cohort Expansion Study of the Safety and Tolerability of Elotuzumab (BMS-901608) Administered in Combination with either Lirilumab (BMS-986015) or Urelumab (BMS-663513) in Subjects with Multiple Myeloma
Wayne Clark IRB00011170 Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial
Christopher Ryan IRB00011171 A Phase 3, Randomized, Open-Label Study of Nivolumab Combined with Ipilimumab Versus Sunitinib Monotherapy in Subjects with Previously Untreated, Advanced or Metastatic Renal Cell Carcinoma
Nicole Marshall IRB00011175 Maternal Body Composition Regulates Placental Function and Fetal Growth
Aaron Ziegler IRB00011177 Effects of neural respiratory drive on laryngeal function during physical activity
Atulya Deodhar IRB00011216 A Multicenter, Randomized, Double-Blind, Placebo-Controlled 24-Week Study Followed by Long-Term Evaluation of Efficacy and Safety of Ixekizumab (LY2439821) in Biologic Disease-Modifying Antirheumatic Drug-Experienced Patients with Active Psoriatic Arthritis
Julie Graff IRB00011227 VA/OHSU (J): A Phase I/II Trial of Concurrent Chemohormonal Therapy Using Enzalutamide (MDV-3100) and Cabazitaxel in Patients with Metastatic Castration Resistant Prostate Cancer
Gina Vaccaro IRB00011256 Phase 2 Study of Preoperative Chemotherapy with Abraxane and Gemcitabine Followed by Chemoradiation for Borderline Resectable or Node-Positive Pancreatic Cancer
Donna Graville IRB00011259 Voice Use and Vocal Effort in Older Adults
Jacqueline Vuky IRB00011260 A Phase II Clinical Trial of Pembrolizumab (MK-3475) in Subjects with Advanced/Unresectable or Metastatic Urothelial Cancer
Arthur Hung IRB00011268 Phase II Randomized Placebo-Controlled Double-Blind Study of Salvage Radiation Therapy (SRT) Plus Placebo Versus SRT Plus Enzalutamide (MDV3100) in Men with High-Risk PSA-Recurrent Prostate Cancer after Radical Prostatectomy
Christopher Ryan IRB00011283 A Randomized Phase 2 Trial of Axitinib and TRC105 Versus Axitinib Alone (Including a Lead-In Phase IB Dose-Escalation Portion) In Patients With Advanced Or Metastatic Renal Cell Carcinoma.
Michael Shapiro IRB00011305 A Randomized, Double-Blind, Placebo-Controlled Phase 3 Study of ISIS 304801 Administered Subcutaneously to Patients with Hypertriglyceridemia (ISIS 304801 CS16 - COMPASS)
Stephen Spurgeon IRB00011311 A Phase 1/2 Proof-of-concept study of the combination of ACP-196 and ACP-319 in subjects with B-cell malignancies
Diane Stadler IRB00011332 Dietary Intake and Behaviors in Adults with Autism Spectrum Disorders
Helmi Lutsep IRB00011352 Multicenter, randomized, double-blind, double-dummy, active-comparator, event-driven, superiority phase III study of secondary prevention of stroke and prevention of systemic embolism in patients with a recent Embolic Stroke of Undetermined Source (ESUS), comparing rivaroxaban 15 mg once daily with aspirin 100 mg (NAVIGATE ESUS)
William Rooney IRB00011378 Investigation of a Novel Biomarker of Cerebral Metabolic Activity in Progressive Forms of Multiple Sclerosis: Trans-Capillary Water Molecule Flux
Helmi Lutsep IRB00011403 A Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Efficacy and Safety of Two Dose Strengths of Dalfampridine Extended Release Tablets for Treatment of Stable Walking Deficits in Post-Ischemic Stroke (MILESTONE)
Deniz Erten-Lyons IRB00011407 A Phase 2a Multi-Center Study of 18F-FDG PET, Safety, and Tolerability of AZD0530 in Mild Alzheimer's Disease
Mark Pennesi IRB00011448 A Multiple-Site, Phase 1/2, Safety and Efficacy Trial of a Recombinant Adeno-associated Virus Vector Expressing Retinoschisin (rAAV2tYF-CB-hRS1) in Patients with X-linked Retinoschisis
Khaled Tolba IRB00011462 A Randomized, Open-Label, Phase I Trial of Continuous, Intermittent, and Pulsatile Selumetinib (AZD6244) plus nab-Paclitaxel as Second-Line Treatment for Stage IIIB or IV Non-Small Cell Lung Cancer (NSCLC)
Kevin Winthrop IRB00011471 A Randomized, Open-Label, Multicenter Study of Liposomal Amikacin for Inhalation (LAI) in Adult Patients with Nontuberculous Mycobacterial (NTM) Lung Infections caused by Mycobacterium avium complex (MAC) that are refractory to treatment
Sarah Feldstein Ewing IRB00011481 Motivational Interviewing and Neuroimaging with Adolescents (MINA)
Elie Traer IRB00011486 A Phase 1, Multicenter, Open-Label, Dose-Escalation, Safety, Pharmacokinetic, Pharmacodynamic, and Clinical Activity Study of Orally Administered AG-221 in Subjects with Advanced Hematologic Malignancies with an IDH2 Mutation
Lara Davis IRB00011533 SARC028: A Phase II Study of the Anti-PD1 Antibody Pembrolizumab (MK-3475) in Patients with Advanced Sarcomas
Henry Milczuk IRB00011538 Developing a National Registry for JORRP (Juvenile Onset Recurrent Respiratory Papillomatosis)
Bayard Lyons IRB00011606 Alzheimer's Comprehensive Treatment Network of Oregon and Washington (ACTNOW!)
Alexey Danilov IRB00011620 A Phase II, Open-Label Study Of Obinutuzumab Plus Bendamustine (BG) In Patients With Previously Untreated Chronic Lymphocytic Leukemia (CLL)
Matthew Taylor IRB00011638 A Phase 2 Proof-of-Concept Study of the Combination of ACP-196 and Pembrolizumab in Subjects with Advanced Head and Neck Squamous Cell Carcinoma
Doria Thiele IRB00011639 Variability of Breast Milk Storage Technique and Impact on Infant Growth
David Spencer IRB00011654 An Open-Label, Safety and Tolerability Study of Chronic Intermittent Use of Diazepam Nasal Spray in Adolescents and Adults with Cluster Seizures
Jonathan Lindner IRB00011664 Assessment of Limb Perfusion with Sonazoid Contrast Ultrasound
Benjamin Ehst IRB00011681 A Phase 3, Multicenter, Randomized, Double-Blind, Parallel-Group, Placebo-And Active-Controlled Study Followed By A Placebo-Controlled Maintenance Period And Open-Label Follow-Up To Evaluate The Efficacy And Safety Of Certolizumab Pegol In Subjects With Moderate To Severe Chronic Plaque Psoriasis
Matthew Taylor IRB00011688 A Phase 1 Study of the Oral TRK Inhibitor LOXO-101 in Adult Patients with Solid Tumors
Christopher Ryan IRB00011698 A Double-blind, Randomized, Placebo-controlled Phase 3 Study of Orally Administered PLX3397 in Subjects with Pigmented Villonodular Synovitis or Giant Cell Tumor of the Tendon Sheath
Charles Lopez IRB00011733 A Phase 2 Proof-of-Concept Study of ACP-196 Alone and in Combination with Pembrolizumab in Subjects with Advanced or Metastatic Pancreatic Cancer
Khaled Tolba IRB00011740 TIGER-3: A Phase 3, Open-label, Multicenter, Randomized Study of Oral Rociletinib (CO 1686) Monotherapy Versus Single-agent Cytotoxic Chemotherapy in Patients with Mutant EGFR Non-small Cell Lung Cancer (NSCLC) after Failure of at Least 1 Previous EGFR-directed Tyrosine Kinase Inhibitor (TKI) and Platinum-doublet Chemotherapy
Gina Vaccaro IRB00011746 I4T-MC-JVDE: Randomized, Double-Blind, Placebo-Controlled, Phase 3 Study of Ramucirumab and Best Supportive Care (BSC) Versus Placebo and BSC as Second-Line Treatment in Patients With Hepatocellular Carcinoma and Elevated Baseline Alpha-Fetoprotein (AFP) Following First-Line Therapy With Sorafenib
Jeremy Cetnar IRB00011749 Randomized Phase 2 Trial of ACP-196 and Pembrolizumab Immunotherapy Dual CHECKpoint Inhibition In Platinum Resistant Metastatic Urothelial Carcinoma (RAPID CHECK study)
Jeffrey Jensen IRB00011751 Pharmacodynamics (Suppression of Ovulation) and Pharmacokinetics Following a Single Subcutaneous Administration of Depo Provera® CI 150 mg/mL, Depo Provera® CI 300mg/2mL, or During Two Cycles of Depo-subQ Provera 104®
Kerri Winters IRB00011765 Health & Mobility in Prostate Cancer Survivors
Khaled Tolba IRB00011778 Protocol D4193C00001: A Phase II, Multi-Center, Single-Arm, Global Study of MEDI4736 Monotherapy in Patients with Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck (SCCHN)
Khaled Tolba IRB00011779 Protocol D4193C00003: A Phase II, Randomized, Open-Label, Multi-Center, Global Study of MEDI4736 Monotherapy, Tremelimumab Monotherapy, and MEDI4736 in Combination with Tremelimumab in Patients with Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck (SCCHN)
Alison Edelman IRB00011784 Determining the impact of combined hormonal contraceptives on ulipristal acetate
Stephen Spurgeon IRB00011800 Intergroup Randomized Phase II Four Arm Study In Patients With Previously Untreated Mantle Cell Lymphoma Of Therapy With: Arm A = Rituximab+ Bendamustine Followed By Rituximab Consolidation (RB → R); Arm B = Rituximab + Bendamustine + Bortezomib Followed By Rituximab Consolidation (RBV→ R), Arm C = Rituximab + Bendamustine Followed By Lenalidomide + Rituximab Consolidation (RB → LR) or Arm D = Rituximab + Bendamustine + Bortezomib Followed By Lenalidomide + Rituximab Consolidation (RBV → LR)
Nir Modiano IRB00011801 A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled Trial of Oral RPC1063 as Induction and Maintenance Therapy for Moderate to Severe Ulcerative Colitis
Matthew Taylor IRB00011804 A Multicenter, Open-Label Phase 1b/2 Trial of Lenvatinib (E7080) Plus Pembrolizumab in Subjects With Selected Solid Tumors
Michelle Cameron IRB00011805 PVAMC / OHSU J: Comprehensive Fall Prevention and Detection in MS
Barry Oken IRB00011847 Meditation or Health & Wellness Education via Internet for Adults 50-80 Years Old
Anna Bar IRB00011848 A Multicenter, Double-blind, Placebo-controlled, Adaptive Phase 3 Trial of POL-103A Polyvalent Melanoma Vaccine in Post-resection Melanoma Patients with a High Risk of Recurrence
Victoria Holiday IRB00011875 Buspirone, in combination with amantadine, for the treatment of levodopa-induced dyskinesia
Eric Simpson IRB00011890 A Phase 2 Multicenter Study to Evaluate the Safety, Pharmacokinetics, and Preliminary Efficacy of Asimadoline in Adult Subjects with Pruritus Associated with Atopic Dermatitis
Akram Khan IRB00011892 A phase III, 52 week, randomized, double-blind, 3-arm parallel group study, comparing the efficacy, safety and tolerability of the fixed dose triple combination FF/UMEC/VI with the fixed dose dual combinations of FF/VI and UMEC/VI, all administered once-daily in the morning via a dry powder inhaler in subjects with chronic obstructive pulmonary disease
Brandon Hayes-Lattin IRB00011894 Protocol CCTL019B2206: A multicenter study of apheresis collection of peripheral blood mononuclear cells (PBMC) in patients with CD19 expressing malignancies who could be eligible for a CTL019 clinical research trial
Daniel Sedehi IRB00011909 An open label, randomized study to determine the rate of cardiovascular events at 1 year for patients with elevated troponins post major non-cardiac surgery and the impact of ticagrelor versus aspirin on the occurrence of cardiovascular events
Jeffrey Jensen IRB00011913 A Phase 3, single arm, clinical trial to study the contraceptive efficacy and safety of the MK-8342B (etonogestrel + 17β-estradiol) vaginal ring in healthy women 18 years of age and older, at risk for pregnancy.
Richard Maziarz IRB00011943 CCTL019C2201 A Multicenter Trial to Determine the Efficacy and Safety of CTL019 in adult patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL)
Brandon Hayes-Lattin IRB00011960 Long Term Follow-Up of Patients Exposed to Lentiviral- Based CD19 directed CART Cell Therapy
Khaled Tolba IRB00011967 An open label, multicenter, phase 2 study to determine the safety and efficacy of BIND-014 (docetaxel nanoparticles for injectable suspension) as a second-line therapy for patients with KRAS mutation positive or Squamous cell non-small cell lung cancer
Eric Simpson IRB00011986 A Phase 2a, Randomized, Double-blinded, Placebo-controlled Study to Evaluate the Efficacy and Safety of MEDI9929 in Adult Subjects with Moderate-to-Severe Atopic Dermatitis
Matthew Taylor IRB00012008 CPDR001X2101: Open Label Multicenter Phase I/II Study of the Safety and Efficacy of PDR001 Administered to Patients with Advanced Malignancies
Stephen Heitner IRB00012026 [MOU-Vanderbilt-IRBShare] Exercise in Genetic Cardiovascular Conditions
Lara Davis IRB00012039 Sarcoma Survivorship Registry
Robert Martindale IRB00012050 A Post-Market, Prospective, Multicenter, Single-Arm Trial of XenMatrix™ AB Surgical Graft in All CDC Wound Class Ventral or Incisional Midline Hernias
Michael Heinrich IRB00012061 A Phase 1 Study of BLU-285 in Patients with Gastrointestinal Stromal Tumors (GIST) and other Relapsed and Refractory Solid Tumors
Marian Smith IRB00012075 Looking at Chronic Fatigue Syndrome through a New Lens: Establishing Objective Diagnostic Criteria for Systemic Exertion Intolerance Disease
Lara Davis IRB00012076 A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Trial of Doxorubicin plus Olaratumab versus Doxorubicin plus Placebo in Patients with Advanced or Metastatic Soft Tissue Sarcoma
Jacqueline Vuky STUDY00015006 A Phase III, Double-Blind Placebo-Controlled, Randomized Study of Taselisib plus Fulvestrant Versus Placebo Plus Fulvestrant in Postmenopausal Women with Estrogen Receptor-Positive and HER2-Negative Locally Advanced or Metastatic Breast Cancer who have Disease Recurrence or Progression During or After Aromatase Inhibitor Therapy.
Laurie King STUDY00015010 PVAMC/OHSU J: Rehabilitation of Central Sensory Impairments for Balance in mTBI
Alexey Danilov STUDY00015069 A randomized phase III study of Bendamustine plus Rituximab versus Ibrutinib plus Rituximab versus Ibrutinib alone in untreated older patients (≥ 65 years of age) with Chronic Lymphocytic Leukemia (CLL)
MinKyoung Song STUDY00015075 Healthy Parents, Healthy Families
Gina Vaccaro STUDY00015077 9785-CL-3021: A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of Enzalutamide in Subjects with Advanced Hepatocellular Carcinoma
Gabrielle Meyers STUDY00015127 A Randomized, Parallel-Cohort Phase I Study of INCB039110 in Combination with Corticosteroids for the Treatment of Acute Graft-Versus-Host Disease
Steven Shea STUDY00015145 Sleep, inactivity, circadian rhythms and cardiovascular risk
Arpana Naik STUDY00015164 A Randomized Phase III Trial Comparing Axillary Lymph Node Dissection to Axillary Radiation in Breast Cancer Patients (cT1-3 N1) Who have Positive Sentinel Lymph Node Disease After Neoadjuvant Chemotherapy
Antonio Frias STUDY00015196 Functional imaging of human placenta by MRI
Matthew Taylor STUDY00015206 An Open-Label, Multicenter, Global Phase 2 Basket Study of Entrectinib for the Treatment of Patients with Locally Advanced or Metastatic Solid Tumors that Harbor NTRK1/2/3, ROS1, or ALK Gene Rearrangements
Peter Jacobs STUDY00015228 A randomized, three-way, cross-over study to assess the impact of nocturnal hypoglycemia on sleep in patients with Type 1 diabetes.
Jeremy Cetnar STUDY00015245 S1314: A Randomized Phase II Study of Co-Expression Extrapolation (COXEN) With Neoadjuvant Chemotherapy for Localized, Muscle-Invasive Bladder Cancer
Jeffrey Jensen STUDY00015294 A dose-finding study to evaluate serum estradiol levels with use of contraceptive vaginal rings releasing Nestorone® and escalating doses of estradiol in normal cycling women
Kim-Hien Dao STUDY00015363 WEAR in Oregon: Defining risks of blood cancer development in a cohort of older women with clonal hematopoiesis and TET2 mutations. (Women Engaged in Advancing health Research in Oregon is a prospective epidemiology study)
Joseph El Youssef STUDY00015452 Testing and Tuning a Multiparameter Exercise Detection Algorithm
 

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Email: trials@ohsu.edu
Call: 503-494-1080