Pilot Study for the Identification of Candidate Urinary Biomarkers for Hepatocellular Carcinoma

Principal Investigator

Charles Thomas

Study Purpose

The primary purpose of this study is find urine biomarkers for the detection of hepatocellular carcinoma. For this, we need urine samples from patients with and without hepatocellular carcinoma. Ideally, urine biomarkers could be used for the screening of hepatocellular carcinoma with a broadly available, inexpensive test. Screening patients at risk for hepatocellular carcinoma is important because the earlier the cancer is detected, the easier it is to treat and the better the chance of survival.

Medical Condition(s)

Hepatocellular carcinoma

Eligibility Criteria

At least 18 years old
Fit into one of the following categories:
-Have hepatocellular carcinoma and have cirrhosis
-Have hepatocellular carcinoma but do not have cirrhosis
-Do not have hepatocellular carcinoma but do have cirrhosis
-Do not have hepatocellular carcinoma and do not have cirrhosis or risk factors for these
No other cancer history
Not currently under treatment for liver disease
Creatinine less than or equal to 1.5mg/dL in the last 3 months

Age Range

18 - 100

Healthy Volunteers Needed


Duration of Participation

One time urine sample collection

Minors Included



Christina Binder


Recruitment End


Compensation Provided


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