IRB #

STUDY00016475

Title

A Master Protocol for Biomarker-Based Treatment of AML (The Beat AML Trial)

Principal Investigator

Uma Borate

Study Purpose

The Leukemia & Lymphoma Society (LLS) is leading this ground-breaking approach to improve cancer treatment. This trial, which will be led and managed by LLS, will take place at many academic research institutions throughout the U.S.A. LLS's goal is to test a number of drugs or drug combination in development to speed up approval and increase effectiveness of treatments for patients diagnosed with AML.

Medical Condition(s)

Acute Leukemia, new diagnosis and relapsed/refractory

Eligibility Criteria

*Adults age 60 or older at the time of diagnosis

*Previously untreated AML with no prior treatment other than hydroxyurea. Prior therapy for myelodysplastic syndrome (MDS), Myeloproliferateive syndromes (MPD) or aplastic anemia is permitted but not with Hypomethylating agents

OR

*If your AML came back after treatment or did not respond to prior therapy for AML.

Age Range

60 - n/a

Healthy Volunteers Needed

No

Duration of Participation

Participation will be dependent on enrollment to the sub study treatment trial associated with this master (umbrella) protocol. the sub studies will include a 7 day screening period, treatment period and follow-up 28 days after the treatment period ends. All subjects who discontinue treatment for any reason other than progressive disease or withdrawal of consent will be contacted every 90 days for information on their medical history for up to 5 years after study enrollment.

Minors Included

No

Contact

Clinical Trials Information Line
Phone: 503-494-1080
Email: trials@ohsu.edu

Sponsor

Beat AML, LLC, a division of the Leukemia and Lymphoma Society, Inc

Recruitment End

01/01/2036

Compensation Provided

No


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