OHSU

IRB #

IRB00010177

Title

A Phase I, Open-Label, Multiple-Ascending Dose Trial to Investigate the Safety, Tolerability, Pharmacokinetics, Biological and Clinical Activity of MSB0010718C in Subjects with Metastatic or Locally Advanced Solid Tumors and Expansion to Selected Indications

Principal Investigator

Matthew Taylor

Study Purpose

The purpose of this study is to test MSB0010718C at different dose levels to see if it is safe and well tolerated when given once every two weeks.

Medical Condition(s)

1. Non-small cell lung cancer
2. Metastatic breast cancer
3. Colorectal cancer
4. Castrate-resistant prostate cancer
5. Melanoma
6. Ovarian cancer

Eligibility Criteria

1. Males and females at least 18 years or older
2. Diagnosis of one of the six cancer types listed above.
3. No history of cancer that has spread to the central nervous system.
4. Other criteria may apply.

Age Range

18 - 100

Healthy Volunteers Needed

No

Duration of Participation

Until your cancer gets worse or you develop unacceptable side effects

Minors Included

No

Contact

Knight Information Line
503-494-1080

Sponsor

EMD Serono, Inc.

Recruitment End

12/31/2014

Compensation Provided

No


Go Back