OHSU

IRB #

IRB00010101

Title

Circadian rhythms and cardiovascular risk

Principal Investigator

Steven Shea

Study Purpose

The purpose of this study is to understand how behaviors (such as exercise and changes in posture) and the effects of the body’s internal clock (called the circadian pacemaker) affect the control of the heart and blood pressure in persons with and without sleep apnea.

Medical Condition(s)

Obstructive sleep apnea (OSA)

Eligibility Criteria

1. Age 40-80 years old
2. BMI less than 40
3. Moderate to severe OSA (AHI)>15
4. No current or previous pharmacological treatment for hypertension

Age Range

40 - 80

Healthy Volunteers Needed

Yes

Duration of Participation

Approximately 6 weeks total:
1-2 week for screening (2-3 visits)
2-3 weeks ambulatory monitoring
5 day in-clinic stay

Minors Included

No

Contact

Sally Roberts
503-418-0949
robersal@ohsu.edu
or
Noal Clemons
503-418-0959
clemonsn@ohsu.edu

Sponsor

Internally funded through the Oregon Institute of Occupational Health Sciences.

Recruitment End

Compensation Provided

Yes

Compensation

Screening Portion: $25 for initial screening visit, $25 for physical exam = up to $50

At home monitoring: $25/week for at home screening, $25 for return of activity monitors = up to $100

In-Patient Stay (5-day): $240 per day = up to $1,200

Study completion bonus = $650

Total Compensation: up to $2,000


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