OHSU

IRB #

IRB00009960

Title

Therapeutic effects of intranasally-administered insulin in adults with amnestic mild cognitive impairment (aMCI) or mild Alzheimer’s disease (AD) ADC-046-INI

Principal Investigator

Deniz Erten-Lyons

Study Purpose

The purpose of this study is to learn more about Alzheimer’s disease using a called Humulin R which is an intranasally-administered insulin. The purpose of this study is to examine the effects of the study drug on cognition, certain parts of the brain and cerebrospinal fluid in subjects with mild cognitive impairment and Alzheimer’s disease.

Medical Condition(s)

Alzheimer's disease

Eligibility Criteria

Diagnosis of Alzheimer's disease. Age 55-85. Generally good health. Able to make frequent visits to OHSU with caregiver/family member. Admission into this study will be based on memory testing and an MRI scan as well as a physical and neurological exam.

Age Range

55 - 85

Healthy Volunteers Needed

No

Duration of Participation

This study requires 11 visits to the clinic and will take 18 months to complete.

Minors Included

No

Contact

Monika Stanko, RN (503)494-7615

Sponsor

National Institute on Aging

Recruitment End

06/02/2014

Compensation Provided

No


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