International Study of Comparative Health Effectiveness with Medical and Invasive Approaches (ISCHEMIA)
The purpose of this study is to compare two standard treatments for cardiac ischemia, or narrowed heart arteries due to the buildup of cholesterol. One treatment is conservative and includes medicines and healthy lifestyle counseling. The other treatment is invasive and includes a procedures to help improve blood flow through the arteries of the heart (called cardiac catheterization, or cardiac cath). The cardiac cath may then require further procedure(s) to improve blood flow. These procedures are routinely done in people with narrowed heart arteries.
Subjects who do not qualify for the ISCHEMIA study may be eligible to participate in a separate, but related, study called CIAO-ISCHEMIA.
At least 21 years old
Diagnosis of at least moderate cardiac ischemia
21 - 100
Healthy Volunteers Needed
Duration of Participation
A year and a half to 6 years, depending on when you enroll
Aynun Naher, Study Coordinator
Funded by National Heart, Lung, and Blood Institute (NHLBI)
Coordinating Centers: Cardiovascular Clinical Research Center of New York University School of Medicine, and Duke Clinical Research Institute
You will receive $20 per study visit beginning with randomization (assignment to conservative or invasive treatment group).