IRB #

IRB00008780

Title

Protocol T: A Comparative Effectiveness Study of Intravitreal Aflibercept, Bevacizumab and Ranibizumab for Diabetic Macular Edema

Principal Investigator

Andreas Lauer

Study Purpose

The primary objective of the proposed research is to compare the efficacy and safety of (1) intravitreal aflibercept, (2) intravitreal bevacizumab, and (3) intravitreal ranibizumab when given to treat central-involved DME in eyes with visual acuity of 20/32 to 20/320.

Medical Condition(s)

Diabetic macular edema (DME)

Eligibility Criteria

1. Age ≥ 18 years
2. Diagnosis of diabetes mellitus (type 1 or type 2)
3. At least one eye meets certain study eye criteria such as vision being 20/32-20/320 & having central involved DME

Age Range

18 - 100

Healthy Volunteers Needed

No

Duration of Participation

2 years

Minors Included

No

Contact

Mitchell Schain
503-494-3115

Sponsor

Jaeb Center for Health Research

Recruitment End

06/01/2013

Compensation Provided

Yes

Compensation

$25 per study visit; maximum $625