A Randomized, Double-Blind, Placebo-Controlled Study of the Safety and Efficacy of Intranasal Midazolam (USL261) in the Outpatient Treatment of Subjects with Seizure Clusters ARTEMIS-1: Acute Rescue Therapy in Epilepsy with Midazolam Intranasal Spray-1
To examine the efficacy and safety of a new drug midazolam IN (taken intranasal- through a nose spray) when taken with a subjects' regular seizure medications to see if it can help cluster seizures.
Partial or generalized epilepsy; with a history of seizure clusters
Male and Females, 14 to 65, with an established diagnisis of partial or generalized epilepsy with cluster seizures. This subjects must also have a dedicated caregiver willing to participate in the study
14 - 65
Healthy Volunteers Needed
Duration of Participation
Variable depending on frequency of seizures. Assuming an average of 4 seizure clusters a year most subjects will complete the study in about 4 months after starting the study drug.
Rebecca Hoffenberg 503.494.9633
Upsher-Smith Laboratories, Inc