OHSU

IRB #

IRB00008575

Title

PVAMC / OHSU J: Risky Decision Making in Methamphetamine Users: The Role of Opioid Blockade

Principal Investigator

Philip Korthuis

Study Purpose

The purpose of this study is to learn more about how a medication called naltrexone might effect risky decision-making in methamphetamine users. Participants will receive a one-time injection of naltrexone or a placebo, and will undergo 2 MRI scans.

Medical Condition(s)

Methamphetamine use, risky decision-making

Eligibility Criteria

Eligible subjects are men and women between the ages of 18 and 55, who are interested in stopping methamphetamine use. Subjects cannot be dependent on any other drugs, except tobacco and caffeine. They may not currently use, or have abused in the the last 5 years, any opioids (which includes heroin, methadone, buprenorphine, oxycodone/OxyContin/Percocet, Vicodin, morphine, codeine, and others). Subjects cannot have had a serious medical illness in the past 30 days, as assessed by study physician upon physical exam.

Age Range

18 - 55

Healthy Volunteers Needed

No

Duration of Participation

5 weeks.

Minors Included

No

Contact

Britta Tremblay. 503-721-7964

Sponsor

National Institute on Drug Abuse

Recruitment End

12/16/2014

Compensation Provided

Yes

Compensation

$200 plus an additional $0 to $280 possible.


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