Developmental Origins of Attention Deficit Hyperactivity Disorder

Principal Investigator

Joel Nigg

Study Purpose

This is a study evaluating the relationship between nutrition, stress, toxins and Attention Deficit Hyperactivity Disorder (ADHD) development. We are looking to see if the foods women eat, the medications they take, or the life stress they undergo when they are pregnant have an effect on the development of ADHD in their unborn children. We will study their children from birth to 7 years old to see if the foods they eat, the medications they take, their family stressors, or their genetics have an effect on the development of ADHD or other behavioral disorders.

Medical Condition(s)

This study will examine the mother's diet during the second and third trimesters of pregnancy. If chosen for the nutritional intervention, the participant will be placed on a non-restrictive healthy diet for the duration of their third trimester. Within 30 days of delivery, the infant will be brought in for a neonatal MRI to evaluate cognitive development. We will continue evaluating the child's development by having the families come in for behavior assessment visits until the child is 4 years old.

Eligibility Criteria

18 years of age or older
Currently less than 22 weeks pregnant or recently gave birth to healthy child
In General Health
May have a history of ADHD symptoms (hyperactivity, impulsivity, and/or problems paying attention)

Age Range

30 - 86

Healthy Volunteers Needed


Duration of Participation

7 years longitudinal study

Minors Included



Research Coordinator: Ceri Sullivan
phone: 503-418-8249


OHSU Foundation
OHSU Department of Psychiatry

Recruitment End


Compensation Provided



Initial visit: $30
Questionnaires: $30
Short Counseling sessions: $10/each (2)
Delivery: $10
Nutritional Phone Interviews: $20/each (4)
3-month Phone Interview: $30
6-month $50
12-15 month $50
24-month $70
36-month $300
48-month $300
60-month $200
72-month $200
84-month $300
Post-Natal Phone Check-Ins $15
48M-Teacher Questionnaire Packet $10
60M-Teacher Questionnaire Packet $10
72M-Teacher Questionnaire Packet $10
84M-Teacher Questionnaire Packet $10

TOTAL: $2,035.00

* In the event that the structured interview is repeated or is completed separately from an onsite or remote visit, participants will be compensated an additional $30 for the interview.

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