The Hatfield Research Center, home to the Layton Center Oak tree by the lake Medical tools of the trade Head statue in front of the School of Neurosciences Computer screen and typing hands entering data
Layton home research cores clinical core education resources data & tissue resources
Dementia Prevention Study (DPS)
Center
Information
publications
events calendar
volunteering for clinical studies
brain images
Alzheimer's Update newsletter
links of interest
contact us
DPS Information
oregon center for complementary and alternative medicine in neurological disorders (ORCCAMIND)
national center for complementary and clternative medicine
10 things to know about evaluating medical resources on the web
dps publications
personnel

Preventing dementia is a high priority goal for our aging population. The Dementia Prevention Study is a 42-month research trial investigating whether standardized gingko biloba extract (GBE) may prevent or delay cognitive decline in people age 85 years or older (the oldest old). The study focuses on the oldest old because they are at particularly high risk for developing mild cognitive impairment (MCI), a precursor to dementia. Because this is a population that has been previously

been out of the mainstream for use of alternative medicine, the safety of GBE in this age group will also be tested in this study.

This pilot study is viewed as a necessary first step in order to demonstrate whether GBE, an alternative or complimentary therapy, has a disease modifying effect on the brain, distinct from a symptomatic effect. Biological effects will be assessed with volumetric quantitative MRI, a means of confirming whether there is a brain modifying effect
(measured as a decrease in brain volume loss with treatment).

One-hundred thirty-three elderly subjects with no history of memory problems and of average physical health were enrolled in the study, which has recently concluded. The study findings have been submitted for professional publication; please check back for the citation.

Sunrise behind Mount Hood