Research Study Opportunity

APPROVED: Aug 9,2006

Research Study of Melatonin Rhythms in Blind Individuals:

The Sleep and Mood Disorders Laboratory at Oregon Health & Science University (OHSU) is seeking blind individuals with no light perception to screen for participation in one of our two research studies. The common goal of the studies is to investigate the hormone melatonin and its potential benefits as a treatment for the nighttime sleep difficulties and daytime sleepiness frequently experienced by blind individuals. Study #1029 includes blind individuals ages 21 to 100 years, and study #0194 includes blind individuals ages 55 to 100 years.

The studies require frequent blood and/or saliva collection periods, which will usually occur at the OHSU Oregon Clinical and Translational Research Institute (OCTRI).. Most collection periods will last for 26 hours, and they will usually be about 2 to 4 weeks apart. Although no specific time commitment will be required, participants may be invited to continue collections for years. Both studies may require the participants to take a daily capsule of either melatonin or placebo. All test are performed at no charge to the participants. Participants will be compensated for each blood/saliva collection, and transportation will be provided free of charge. For more information, please call Amber at 503-494-4677.

OHSU IRB #1029
protocol expiration: 1/14/2010

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