Photo of William H. Fleming, M.D., Ph.D.

William H. Fleming M.D., Ph.D.

    • Professor of Pediatrics School of Medicine
    • Cancer Biology Graduate Program School of Medicine
    • Cell and Developmental Biology Graduate Program School of Medicine

Dr. Fleming received both his medical degree and Ph.D. from the University of Manitoba, Winnipeg, in 1987. His specialty is bone marrow transplantation, and he is board certified in internal medicine and medical oncology. His research interests include stem-cell research, bone marrow transplantation, growth factors, and in utero transplantation. Dr. Fleming completed his residency and fellowship training at Stanford University.

  • Residency:

    • 1987- 89 Stanford University Hospital, Stanford
  • Fellowship:

    • 1989- 93 Stanford University Hospital, Stanford
  • Certifications:

    • Internal medicine, medical oncology

Memberships and associations

  • Internal medicine, 1995

Publications

  • "The corepressor Rcor1 is essential for normal myeloerythroid lineage differentiation." Stem Cells In: , Vol. 33, No. 11, 01.11.2015, p. 3304-3314.
  • "The triterpenoid RTA 408 is a robust mitigator of hematopoietic acute radiation syndrome in mice." Radiation Research In: , Vol. 183, No. 3, 01.03.2015, p. 338-344.
  • "Intestinal microbiota-derived metabolomic blood plasma markers for prior radiation injury." International Journal of Radiation Oncology Biology Physics  In: , Vol. 91, No. 2, 2015, p. 360-367.
  • "Functional integration of acute myeloid leukemia into the vascular niche." Leukemia In: , Vol. 28, No. 10, 01.10.2014, p. 1978-1987.
  • "Corepressor Rcor1 is essential for murine erythropoiesis." Blood  In: , Vol. 123, No. 20, 15.05.2014, p. 3175-3184.
  • "HCMV Infection of Humanized Mice after Transplantation of G-CSF-Mobilized Peripheral Blood Stem Cells from HCMV-Seropositive Donors." Biology of Blood and Marrow Transplantation In: , Vol. 20, No. 1, 01.2014, p. 132-135.
  • "Kinase pathway dependence in primary human leukemias determined by rapid inhibitor screening." Cancer Research In: , Vol. 73, No. 1, 01.01.2013, p. 285-296.
  • "Endothelial cells mitigate DNA damage and promote the regeneration of hematopoietic stem cells after radiation injury." Stem Cell Research In: , Vol. 11, No. 3, 2013, p. 1013-1021.
  • "Multiplex high-throughput gene mutation analysis in acute myeloid leukemia." Human Pathology  In: , Vol. 43, No. 12, 12.2012, p. 2167-2176.
  • "A novel human cytomegalovirus locus modulates cell type-specific outcomes of infection." PLoS Pathogens  In: , Vol. 7, No. 12, e1002444, 12.2011.
  • "Fancd2-/- mice have hematopoietic defects that can be partially corrected by resveratrol." Blood  In: , Vol. 116, No. 24, 09.12.2010, p. 5140-5148.
  • "Granulocyte-colony stimulating factor reactivates human cytomegalovirus in a latently infected humanized mouse model." Cell Host and Microbe In: , Vol. 8, No. 3, 16.09.2010, p. 284-291.
  • "Endothelial cells mediate the regeneration of hematopoietic stem cells." Stem Cell Research In: , Vol. 4, No. 1, 01.2010, p. 17-24.
  • "BMP4 regulates the hematopoietic stem cell niche." Blood In: , Vol. 114, No. 20, 12.11.2009, p. 4393-4401.
  • "Apoptosis-stimulating protein of p53 (ASPP2) heterozygous mice are tumor-prone and have attenuated cellular damage-response thresholds." Proceedings of the National Academy of Sciences of the United States of America In: , Vol. 106, No. 11, 17.03.2009, p. 4390-4395.
  • "Hematopoietic stem cells contribute to lymphatic endothelium." PLoS One In: , Vol. 3, No. 11, e3812, 26.11.2008.
  • "Transvection mediated by the translocated cyclin D1 locus in mantle cell lymphoma." Journal of Experimental Medicine  In: , Vol. 205, No. 8, 04.08.2008, p. 1843-1858.
  • "Myeloid lineage progenitors give rise to vascular endothelium." Proceedings of the National Academy of Sciences of the United States of America In: , Vol. 103, No. 35, 29.08.2006, p. 13156-13161.
  • "Bone marrow-derived cells fuse with normal and transformed intestinal stem cells." Proceedings of the National Academy of Sciences of the United States of America In: , Vol. 103, No. 16, 18.04.2006, p. 6321-6325.
  • "In vivo genetic selection of renal proximal tubules." Molecular Therapy  In: , Vol. 13, No. 1, 01.2006, p. 49-58.
  • "Mouse models of hematopoietic engraftment : Limitations of transgenic green fluorescent protein strains and a high-performance liquid chromatography approach to analysis of erythroid chimerism." Stem Cells In: , Vol. 24, No. 9, 2006, p. 2045-2051.
  • "Endothelial cell-specific markers : Going . . . going . . . gone." Blood In: , Vol. 106, No. 3, 01.08.2005, p. 769.
  • "Donor marker infidelity in transgenic hematopoietic stem cells." Stem Cells In: , Vol. 23, No. 5, 05.2005, p. 638-643.
  • "The hereditary hemochromatosis protein, HFE, lowers intracellular iron levels independently of transferrin receptor 1 in TRVb cells." Blood In: , Vol. 105, No. 6, 15.03.2005, p. 2564-2570.
  • "Transplanted human bone marrow contributes to vascular endothelium." Proceedings of the National Academy of Sciences of the United States of America In: , Vol. 101, No. 48, 30.11.2004, p. 16891-16896.
  • "PECAM-1 is expressed on hematopoietic stem cells throughout ontogeny and identifies a population of erythroid progenitors." Blood In: , Vol. 104, No. 4, 15.08.2004, p. 1010-1016.
  • "Myelomonocytic cells are sufficient for therapeutic cell fusion in liver." Nature Medicine  In: , Vol. 10, No. 7, 07.2004, p. 744-748.
  • "Transplanted adult hematopoietic stems cells differentiate into functional endothelial cells." Blood In: , Vol. 103, No. 1, 01.01.2004, p. 13-19.
  • "Activation of the G-CSF and Flt-3 receptors protects hematopoietic stem cells from lethal irradiation." Experimental Hematology In: , Vol. 31, No. 11, 11.2003, p. 1119-1125.
  • "Converging roads : Evidence for an adult hemangioblast." Experimental Hematology In: , Vol. 31, No. 11, 11.2003, p. 987-993.

Additional information

Edit profile