Photo of Wayne Marsdon Clark, M.D.

Wayne Marsdon Clark M.D.

Dr. Clark is a professor of neurology at the Dotter Interventional Institute and the director of the OHSU Stroke Center. Dr. Clark received his medical degree from Oregon Health & Sciences University and completed his neurology residency and stroke fellowship at the University of California at San Diego. Dr. Clark`s clinical interest is in the acute treatment of stroke, including the investigation of new potential stroke therapies.

  • Residency:

    • Neurology: University of California, San Diego, CA
  • Fellowship:

    • Stroke: University of California, San Diego, CA
  • Certifications:

    • 1986

Memberships and associations

  • Neurology

Publications

  • "Safety and efficacy of multipotent adult progenitor cells in acute ischaemic stroke (MASTERS) : a randomised, double-blind, placebo-controlled, phase 2 trial." The Lancet Neurology In: , Vol. 16, No. 5, 01.05.2017, p. 360-368.
  • "Combined intravenous Thrombolysis and Thrombectomy vs Thrombectomy alone for acute ischemic stroke : A pooled analysis of the SWIFT and STAR studies." JAMA Neurology In: , Vol. 74, No. 3, 01.03.2017, p. 268-274.
  • "Pioglitazone after ischemic stroke or Transient Ischemic attack." New England Journal of Medicine In: , Vol. 374, No. 14, 07.04.2016, p. 1321-1331.
  • "Effects of Acute Stroke Serum on Non-Ischemic Cerebral and Mesenteric Vascular Function." Translational Stroke Research In: , Vol. 7, No. 2, 01.04.2016, p. 156-165.
  • "Rapid learning curve for Solitaire FR stent retriever therapy : Evidence from roll-in and randomised patients in the SWIFT trial." Journal of NeuroInterventional Surgery In: , Vol. 8, No. 4, 01.04.2016, p. 347-352.
  • "Long-term results of stenting versus endarterectomy for carotid-artery stenosis." New England Journal of Medicine In: , Vol. 374, No. 11, 17.03.2016, p. 1021-1031.
  • "Characteristics of participants consenting versus declining follow-up for up to 10 years in a randomized clinical trial." Clinical Trials In: , Vol. 12, No. 6, 01.12.2015, p. 657-663.
  • "Determinants of intracranial hemorrhage occurrence and outcome after neurothrombectomy therapy : Insights from the solitaire fr with intention for thrombectomy randomized trial." American Journal of Neuroradiology In: , Vol. 36, No. 12, 01.12.2015, p. 2303-2307.
  • "SOLITAIRE™ with the intention for thrombectomy (SWIFT) trial : Design of a randomized, controlled, multicenter study comparing the SOLITAIRE™ Flow Restoration device and the MERCI Retriever in acute ischaemic stroke." International Journal of Stroke In: , Vol. 9, No. 5, 2014, p. 658-668.
  • "Association of intraprocedural blood pressure and end tidal carbon dioxide with outcome after acute stroke intervention." Neurocritical Care In: , Vol. 20, No. 2, 2014, p. 202-208.
  • "Transcranial laser therapy in acute stroke treatment : Results of neurothera effectiveness and safety trial 3, a phase III clinical end point device trial." Stroke  In: , Vol. 45, No. 11, 2014, p. 3187-3193.
  • "Endovascular therapy after intravenous t-PA versus t-PA alone for stroke." New England Journal of Medicine In: , Vol. 368, No. 10, 07.03.2013, p. 893-903.
  • "Dabigatran etexilate : Management in acute ischemic stroke." American Journal of Critical Care In: , Vol. 22, No. 2, 03.2013, p. 169-176.
  • "Stroke after carotid stenting and endarterectomy in the carotid revascularization endarterectomy versus stenting trial (CREST)." Circulation In: , Vol. 126, No. 25, 18.12.2012, p. 3054-3061.
  • "Safety and efficacy of NA-1 in patients with iatrogenic stroke after endovascular aneurysm repair (ENACT) : A phase 2, randomised, double-blind, placebo-controlled trial." The Lancet Neurology  In: , Vol. 11, No. 11, 11.2012, p. 942-950.
  • "Solitaire flow restoration device versus the Merci Retriever in patients with acute ischaemic stroke (SWIFT) : A randomised, parallel-group, non-inferiority trial." The Lancet In: , Vol. 380, No. 9849, 10.2012, p. 1241-1249.
  • "Costs and cost-effectiveness of carotid stenting versus endarterectomy for patients at standard surgical risk : Results from the Carotid Revascularization Endarterectomy Versus Stenting Trial (CREST)." Stroke In: , Vol. 43, No. 9, 09.2012, p. 2408-2416.
  • "Stroke : Treatment for acute strokeĝ€"the end of the citicoline saga." Nature Reviews Neurology In: , Vol. 8, No. 9, 09.2012, p. 484-485.
  • "Health-related quality of life after carotid stenting versus carotid endarterectomy : Results from CREST (Carotid Revascularization Endarterectomy versus Stenting Trial)." Journal of the American College of Cardiology In: , Vol. 58, No. 15, 04.10.2011, p. 1557-1565.
  • "Boosting enrolment in clinical trials : Validation of a regional network model." Clinical Trials In: , Vol. 8, No. 5, 10.2011, p. 645-653.
  • "Intracranial hemorrhage complicating carotid artery stenting and carotid endarterectomy." Stroke In: , Vol. 42, No. 10, 10.2011, p. 2720-2721.
  • "Matrix metalloproteinase-9 in an exploratory trial of intravenous minocycline for acute ischemic stroke." Stroke In: , Vol. 42, No. 9, 09.2011, p. 2633-2635.
  • "Meta-analysis of randomized intra-arterial thrombolytic trials for the treatment of acute stroke due to middle cerebral artery occlusion." Journal of NeuroInterventional Surgery In: , Vol. 3, No. 2, 06.2011, p. 151-155.
  • "Drug eluting stents for symptomatic intracranial and vertebral artery stenosis." Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences In: , Vol. 17, No. 2, 06.2011, p. 241-247.
  • "Sonothrombolysis : An Emerging Modality for the Treatment of Acute Ischemic and Hemorrhagic Stroke." Translational Stroke Research In: , Vol. 2, No. 2, 06.2011, p. 159-170.
  • "Safety of stenting and endarterectomy by symptomatic status in the Carotid Revascularization Endarterectomy Versus Stenting Trial (CREST)." Stroke In: , Vol. 42, No. 3, 03.2011, p. 675-680.
  • "Potentiating intra-arterial sonothrombolysis for acute ischemic stroke by the addition of the ultrasound contrast agents (Optison™ & SonoVue®)." Journal of Thrombosis and Thrombolysis In: , Vol. 31, No. 1, 01.2011, p. 71-84.
  • "Carotid stenting vs surgery : Parsing the risk of stroke and MI." Cleveland Clinic Journal of Medicine In: , Vol. 77, No. 12, 12.2010, p. 892-902.
  • "Minocycline to Improve Neurologic Outcome in Stroke (MINOS) : A dose-finding study." Stroke In: , Vol. 41, No. 10, 10.2010, p. 2283-2287.
  • "Stenting versus endarterectomy for treatment of carotid-artery stenosis." New England Journal of Medicine In: , Vol. 363, No. 1, 01.07.2010, p. 11-23.

Additional information

Edit profile