Photo of Sudarshan Anand, Ph.D.

Sudarshan Anand Ph.D.

    • Assistant Professor of Cell, Developmental and Cancer Biology School of Medicine
    • Cell and Developmental Biology Graduate Program School of Medicine
    • Cancer Biology Graduate Program School of Medicine
    • Program in Molecular and Cellular Biosciences School of Medicine

Areas of interest

  • MicroRNA, Cancer, Tumor Microenvironment, Cell Engineering

Education

  • Ph.D., Johns Hopkins University, Baltimore Maryland 2007

Publications

  • "Understanding and Resetting Radiation Sensitivity in Rectal Cancer." Annals of Surgery In: , 24.07.2017.
  • "Colorectal Cancer Liver Metastasis : Evolving Paradigms and Future Directions." CMGH Cellular and Molecular Gastroenterology and Hepatology In: , Vol. 3, No. 2, 01.03.2017, p. 163-173.
  • "MicroRNA regulation of endothelial TREX1 reprograms the tumour microenvironment." Nature Communications  In: , Vol. 7, 13597, 25.11.2016.
  • "Kinase-independent role for CRAF-driving tumour radioresistance via CHK2." Nature Communications In: , Vol. 6, 8154, 03.09.2015.
  • "Manipulating MicroRNAs to regulate macrophage polarization in gliomas." Journal of the National Cancer Institute In: , Vol. 106, No. 8, dju230, 01.08.2014.
  • "Manipulating microRNAs to regulate macrophage polarization in gliomas." Journal of the National Cancer Institute In: , Vol. 106, No. 8, 2014.
  • "An integrin β 3-KRAS-RalB complex drives tumour stemness and resistance to EGFR inhibition." Nature Cell Biology In: , Vol. 16, No. 5, 2014, p. 457-468.
  • "Ras pathway inhibition prevents neovascularization by repressing endothelial cell sprouting." Journal of Clinical Investigation  In: , Vol. 123, No. 11, 01.11.2013, p. 4900-4908.
  • "A brief primer on microRNAs and their roles in angiogenesis." Vascular Cell  In: , Vol. 5, No. 1, 2, 2013.
  • "EGFR-dependent pancreatic carcinoma cell metastasis through Rap1 activation." Oncogene In: , Vol. 31, No. 22, 31.05.2012, p. 2783-2793.
  • "EGFR-mediated carcinoma cell metastasis mediated by integrin αvβ5 depends on activation of c-Src and cleavage of MUC1." PLoS One In: , Vol. 7, No. 5, e36753, 07.05.2012.
  • "Expression of anti-HVEM single-chain antibody on tumor cells induces tumor-specific immunity with long-term memory." Cancer Immunology, Immunotherapy  In: , Vol. 61, No. 2, 02.2012, p. 203-214.
  • "Herpesvirus entry mediator regulates hypoxiainducible factor-1α and erythropoiesis in mice." Journal of Clinical Investigation  In: , Vol. 121, No. 12, 01.12.2011, p. 4810-4819.
  • "A MEK-independent role for CRAF in mitosis and tumor progression." Nature Medicine In: , Vol. 17, No. 12, 12.2011, p. 1641-1645.
  • "Emerging Role of Micro-RNAs in the Regulation of Angiogenesis." Genes and Cancer In: , Vol. 2, No. 12, 12.2011, p. 1134-1138.
  • "MicroRNA-mediated regulation of the angiogenic switch." Current Opinion in Hematology In: , Vol. 18, No. 3, 05.2011, p. 171-176.
  • "B7-H1/CD80 interaction is required for the induction and maintenance of peripheral T-cell tolerance." Blood  In: , Vol. 116, No. 8, 26.08.2010, p. 1291-1298.
  • "MicroRNA-132-mediated loss of p120RasGAP activates the endothelium to facilitate pathological angiogenesis." Nature Medicine In: , Vol. 16, No. 8, 08.2010, p. 909-914.
  • "Disruption of angiogenesis and tumor growth with an orally active drug that stabilizes the inactive state of PDGFRβ/B-RAF." Proceedings of the National Academy of Sciences of the United States of America In: , Vol. 107, No. 9, 02.03.2010, p. 4299-4304.
  • "B7-H4-deficient mice display augmented neutrophil-mediated innate immunity." Blood  In: , Vol. 113, No. 8, 19.02.2009, p. 1759-1767.
  • "Selective targeting of the LIGHT-HVEM costimulatory system for the treatment of graft-versus-host disease." Blood  In: , Vol. 109, No. 9, 01.05.2007, p. 4097-4104.
  • "Essential role of TNF family molecule LIGHT as a cytokine in the pathogenesis of hepatitis." Journal of Clinical Investigation  In: , Vol. 116, No. 4, 01.04.2006, p. 1045-1051.
  • "Control of autoimmune diseases by the B7-CD28 family molecules." Current Pharmaceutical Design  In: , Vol. 10, No. 2, 2004, p. 121-128.

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