Photo of Soren Impey, Ph.D.

Soren Impey Ph.D.

  • (503) 494-7540
    • Associate Professor of Pediatrics School of Medicine
    • Cell and Developmental Biology Graduate Program School of Medicine
    • Cancer Biology Graduate Program School of Medicine

1991-1998 Ph.D., University of Washington1998-2000 Postdoctoral Fellow, University of Washington2000-2006 Postdoctoral Fellow, Vollum Institute, OHSU2006-present Assistant Professor, Oregon Stem Cell Center, Dept. of Cell and Developmental biology, OHSU

Education

  • Ph.D., University of Washington, Seattle Washington 1998

Memberships and associations

  • Cell &Developmental Biology Neuroscience Graduate Program Program in Molecular &Cellular Biosciences

Publications

  • "Apolipoprotein E4 and Insulin Resistance Interact to Impair Cognition and Alter the Epigenome and Metabolome." Scientific Reports  In: , Vol. 7, 43701, 08.03.2017.
  • "Short- and long-term effects of Fe irradiation on cognition and hippocampal DNA methylation and gene expression." BMC Genomics  In: , Vol. 17, No. 1, 825, 24.10.2016.
  • "Status epilepticus stimulates NDEL1 expression via the CREB/CRE pathway in the adult mouse brain." Neuroscience  In: , Vol. 331, 07.09.2016, p. 1-12.
  • "Targeted deletion of miR-132/-212 impairs memory and alters the hippocampal transcriptome." Learning and Memory  In: , Vol. 23, No. 2, 01.02.2016, p. 61-71.
  • "Proton irradiation induces persistent and tissue-specific DNA methylation changes in the left ventricle and hippocampus." BMC Genomics  In: , Vol. 17, No. 1, 273, 2016.
  • "RNA sequencing distinguishes benign from malignant pancreatic lesions sampled by EUS-guided FNA." Gastrointestinal Endoscopy In: , 11.11.2015.
  • "Oxymetholone therapy of fanconi anemia suppresses osteopontin transcription and induces hematopoietic stem cell cycling." Stem Cell Reports  In: , Vol. 4, No. 1, 13.01.2015, p. 90-102.
  • "Foxa3 induces goblet cell metaplasia and inhibits innate antiviral immunity." American Journal of Respiratory and Critical Care Medicine In: , Vol. 189, No. 3, 01.02.2014, p. 301-313.
  • "Leptin induces hippocampal synaptogenesis via CREB-regulated MicroRNA-132 suppression of p250GAP." Molecular Endocrinology In: , Vol. 28, No. 7, 2014, p. 1073-1087.
  • "The environmental neurotoxicant PCB 95 promotes synaptogenesis via ryanodine receptor-dependent miR132 upregulation." Journal of Neuroscience In: , Vol. 34, No. 3, 2014, p. 717-725.
  • "Targeting inhibitors of the tumor suppressor PP2A for the treatment of pancreatic cancer." Molecular Cancer Research In: , Vol. 12, No. 6, 2014, p. 924-939.
  • "Profiling status epilepticus-induced changes in hippocampal RNA expression using high-throughput RNA sequencing." Scientific Reports  In: , Vol. 4, 6930, 2014.
  • "Pin1 Regulates the Dynamics of c-Myc DNA Binding To Facilitate Target Gene Regulation and Oncogenesis." Molecular and Cellular Biology In: , Vol. 33, No. 15, 08.2013, p. 2930-2949.
  • "A Genome-Wide Screen of CREB Occupancy Identifies the RhoA Inhibitors Par6C and Rnd3 as Regulators of BDNF-Induced Synaptogenesis." PLoS One In: , Vol. 8, No. 6, e64658, 06.06.2013.
  • "MiRNA-132 : A dynamic regulator of cognitive capacity." Brain Structure and Function  In: , Vol. 218, No. 3, 05.2013, p. 817-831.
  • "Mitogen- and stress-activated kinases regulate progenitor cell proliferation and neuron development in the adult dentate gyrus." Journal of Neurochemistry  In: , Vol. 123, No. 5, 12.2012, p. 676-688.
  • "PCB-95 modulates the calcium-dependent signaling pathway responsible for activity-dependent dendritic growth." Environmental Health Perspectives In: , Vol. 120, No. 7, 06.2012, p. 1003-1009.
  • "Corrigendum to "An activity-induced microRNA controls dendritic spine formation by regulating Rac1-PAK signaling" [YMCNE (2010) 146-156]." Molecular and Cellular Neuroscience In: , Vol. 49, No. 2, 02.2012, p. 250.
  • "Characterization of the CLEAR network reveals an integrated control of cellular clearance pathways." Human Molecular Genetics  In: , Vol. 20, No. 19, ddr306, 10.2011, p. 3852-3866.
  • "KDM5B regulates embryonic stem cell self-renewal and represses cryptic intragenic transcription." EMBO Journal  In: , Vol. 30, No. 8, 20.04.2011, p. 1473-1484.
  • "Fusion between intestinal epithelial cells and macrophages in a cancer context results in nuclear reprogramming." Cancer Research In: , Vol. 71, No. 4, 15.02.2011, p. 1497-1505.
  • "MicroRNA regulation of neural stem cells and neurogenesis." Journal of Neuroscience In: , Vol. 30, No. 45, 10.11.2010, p. 14931-14936.
  • "Regulation of the miR-212/132 locus by MSK1 and CREB in response to neurotrophins." Biochemical Journal  In: , Vol. 428, No. 2, 01.06.2010, p. 281-291.
  • "An activity-induced microRNA controls dendritic spine formation by regulating Rac1-PAK signaling." Molecular and Cellular Neuroscience In: , Vol. 43, No. 1, 01.2010, p. 146-156.
  • "Transgenic miR132 alters neuronal spine density and impairs novel object recognition memory." PLoS One  In: , Vol. 5, No. 11, e15497, 2010.
  • "An activity-regulated microRNA controls dendritic plasticity by down-regulating p250GAP." Proceedings of the National Academy of Sciences of the United States of America  In: , Vol. 105, No. 26, 01.07.2008, p. 9093-9098.
  • "Homeostatic regulation of MeCP2 expression by a CREB-induced microRNA." Nature Neuroscience In: , Vol. 10, No. 12, 12.2007, p. 1513-1514.
  • "A Histone Deacetylase Regulates Addiction." Neuron  In: , Vol. 56, No. 3, 08.11.2007, p. 415-417.
  • "A new binding motif for the transcriptional repressor REST uncovers large gene networks devoted to neuronal functions." Journal of Neuroscience  In: , Vol. 27, No. 25, 20.06.2007, p. 6729-6739.
  • "microRNA Modulation of Circadian-Clock Period and Entrainment." Neuron  In: , Vol. 54, No. 5, 07.06.2007, p. 813-829.

Additional information

Edit profile