Photo of Shannon McWeeney, Ph.D.

Shannon McWeeney Ph.D.

  • (503) 494-8347
    • Professor of Medicine School of Medicine
    • Biomedical Informatics Graduate Program School of Medicine

Statistical Genetics, Computational Biology, Network Reconstruction, Statistical Methodology for functional genomics data, data cleaning and data integration

Education

  • Ph.D., University of California, Berkeley California 2000
  • Residency:

    • PhD (2000) University of California, Berkeley, Statistical GeneticsMSE (2002) University of Pennsylvania, Computational Biology

Publications

  • "Working Memory and Vigilance as Multivariate Endophenotypes Related to Common Genetic Risk for Attention-Deficit/Hyperactivity Disorder." Journal of the American Academy of Child and Adolescent Psychiatry  In: , Vol. 57, No. 3, 01.03.2018, p. 175-182.
  • "Characterization of the leukemogenic potential of distal cytoplasmic CSF3R truncation and missense mutations." Leukemia In: , Vol. 31, No. 12, 01.12.2017, p. 2752-2760.
  • "Comprehensive definition of human immunodominant CD8 antigens in tuberculosis." npj Vaccines In: , Vol. 2, No. 1, 8, 01.12.2017.
  • "Extensive Homeostatic T Cell Phenotypic Variation within the Collaborative Cross." Cell Reports In: , Vol. 21, No. 8, 21.11.2017, p. 2313-2325.
  • "Recurrent cyclin D2 mutations in myeloid neoplasms." Leukemia In: , Vol. 31, No. 9, 01.09.2017, p. 2005-2008.
  • "Unpaired extracellular cysteine mutations of CSF3R mediate gain or loss of function." Cancer Research In: , Vol. 77, No. 16, 15.08.2017, p. 4258-4267.
  • "NFAT5 and SLC4A10 loci associate with plasma osmolality." Journal of the American Society of Nephrology In: , Vol. 28, No. 8, 01.08.2017, p. 2311-2321.
  • "Oas1b-dependent immune transcriptional profiles of west nile virus infection in the collaborative cross." G3: Genes, Genomes, Genetics  In: , Vol. 7, No. 6, 01.06.2017, p. 1665-1682.
  • "Alignment of the transcriptome with individual variation in animals selectively bred for High Drinking-In-the-Dark (HDID)." Alcohol  In: , Vol. 60, 01.05.2017.
  • "A microRNA screen identifies the Wnt signaling pathway as a regulator of the interferon response during flavivirus infection." Journal of Virology In: , Vol. 91, No. 8, e02388-16, 01.04.2017.
  • "Identification of Interleukin-1 by Functional Screening as a Key Mediator of Cellular Expansion and Disease Progression in Acute Myeloid Leukemia." Cell Reports  In: , Vol. 18, No. 13, 28.03.2017, p. 3204-3218.
  • "REST corepressors RCOR1 and RCOR2 and the repressor INSM1 regulate the proliferation- differentiation balance in the developing brain." Proceedings of the National Academy of Sciences of the United States of America  In: , Vol. 114, No. 3, 17.01.2017, p. E406-E415.
  • "Integrated functional and mass spectrometry-based flow cytometric phenotyping to describe the immune microenvironment in acute myeloid leukemia." Journal of Immunological Methods In: , 01.01.2017.
  • "Effects of selection for ethanol preference on gene expression in the nucleus accumbens of HS-CC mice." Genes, Brain and Behavior In: , 2017.
  • "On the relationships in rhesus macaques between chronic ethanol consumption and the brain transcriptome." Addiction Biology  In: , 2017.
  • "Identification of Hip BMD Loss and Fracture Risk Markers Through Population-Based Serum Proteomics." Journal of Bone and Mineral Research In: , 2017.
  • "Integration of genomic, transcriptomic and functional profiles of aggressive osteosarcomas across multiple species." Oncotarget  In: , Vol. 8, No. 44, 2017, p. 76241-76256.
  • "Evidence-Based Precision Oncology with the Cancer Targetome." Trends in Pharmacological Sciences In: , 2017.
  • "A Mouse Model of Chronic West Nile Virus Disease." PLoS Pathogens In: , Vol. 12, No. 11, e1005996, 01.11.2016.
  • "The effect of inhibition of PP1 and TNFα signaling on pathogenesis of SARS coronavirus." BMC Systems Biology In: , Vol. 10, No. 1, 93, 23.09.2016.
  • "Cover Image, Volume 171B, Number 6, September 2016." American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics  In: , Vol. 171, No. 6, 01.09.2016, p. 1.
  • "Does the urinary microbiome play a role in urgency urinary incontinence and its severity?" Frontiers in Cellular and Infection Microbiology  In: , Vol. 6, No. JUL, 78, 27.07.2016.
  • "HitWalker2 : Visual analytics for precision medicine and beyond." Bioinformatics  In: , Vol. 32, No. 8, 15.04.2016, p. 1253-1255.
  • "IL-10 and integrin signaling pathways are associated with head and neck cancer progression." BMC Genomics  In: , Vol. 17, No. 1, 38, 08.01.2016.
  • "Identification and characterization of tyrosine kinase nonreceptor 2 mutations in leukemia through integration of kinase inhibitor screening and genomic analysis." Cancer Research In: , Vol. 76, No. 1, 01.01.2016, p. 127-138.
  • "Pathway analysis in attention deficit hyperactivity disorder : An ensemble approach." American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics  In: , 2016.
  • "Diversity outbred mice at 21 : Maintaining allelic variation in the face of selection." G3: Genes, Genomes, Genetics In: , Vol. 6, No. 12, 2016, p. 3893-3902.
  • "Combined targeting of SET and tyrosine kinases provides an effective therapeutic approach in human T-cell acute lymphoblastic leukemia." Oncotarget  In: , Vol. 7, No. 51, 2016, p. 84214-84227.
  • "Between pathways and networks lies context : Implications for precision medicine." Science Progress  In: , Vol. 98, No. 3, 01.09.2015, p. 253-263.
  • "Use of semantic workflows to enhance transparency and reproducibility in clinical omics." Genome Medicine In: , Vol. 7, No. 1, 73, 25.07.2015.

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